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PROBING SITE-SPECIFIC INTERACTIONS BETWEEN EPIDERMAL GROWTH FACTOR RECEPTOR AND AN ADNECTIN USING HDX-ETD MS APPROACH

 

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DynamX HDX Data Analysis Software 3.0 Simplifying Hydrogen Deuterium Exchange Interpretation P ROT EIN CONFORMAT ION ANALYSIS MADE SIM P LE In HDX MS studies, replicate data are collected across multiple time points and varied species (native vs. mutant, innovator…
Key words
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LOCALIZED CONFORMATION ANALYSES OF MUTATED HUMAN IgG1 BY HYDROGEN DEUTERIUM EXCHANGE MASS SPECTROMETRY AND DIFFERENTIAL SCANNING CALORIMETRY Joomi Ahn 1, Xiaojun Lu2, Colette Quinn3, St John Skilton1, Ying Qing Yu1, and Jihong Wang2 1 Waters Corporation, 2 MedImmune, 3TA Instruments…
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ACQUITY UPLC M-Class System with HDX Technology Integration of Hydrogen Deuterium Exchange with High Resolution MS QUANT IF Y CHANGES IN P ROT EIN CONFORMAT ION W IT H CONFIDENC E The Waters ® ACQUITY UPLC ® M-Class System with…
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Conformational Characterization of Calmodulin by Hydrogen Deuterium Exchange Mass Spectrometry Joomi Ahn, Martha Stapels, Michael Eggertson, Keith Fadgen, and Ying Qing Yu Waters Corporation, Milford, MA, U.S. A P P L I C AT I O N B E N…
Key words
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