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HPLC Enantiomeric Separations of Pharmaceuticals Using Polar Organic Mobile Phases

 

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Basics of Chiral HPLC
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Basics of Chiral HPLC Definitions Principles Available CSPs Mobile phase types T408109 sigma-aldrich.com The Field of Stereochemistry 1. All isomers have same chemical formula but differ in the arrangement of certain chemical groups in space. 2. Many types of isomers…
Key words
chirobiotic, chirobioticionic, ionicphases, phasesphase, phasepolar, polarchiral, chiralcsps, cspsracemates, racematescooh, coohcyclobond, cyclobondselectivity, selectivitynormal, normalinclusion, inclusionmobile, mobilecsp
Sigma-Aldrich Integrated Chiral Services • Paul Rodwell and Thierry Bonnaud Chirality 2012 Fort Worth, Texas, 10th-13th June Agenda • • • • • • • • Introduction Sigma-Aldrich Integrated Chiral Services Capability SAFC Pharmorphix® Chiral Services Overview Chiral Method Development…
Key words
chiral, chiralphenylglycinol, phenylglycinolmandelate, mandelatecrystallisation, crystallisationsalt, saltscale, scaleconglomerate, conglomeratepharmorphix, pharmorphixsmb, smbdiffraction, diffractionservices, servicesdevelopment, developmentcrystal, crystaldiastereomeric, diastereomericxrpd
A Novel Approach in HPLC Chiral Method Development: Dealing with Multiple Chiral Centers David S. Bell1, Anders Fridstrom2, and Gaurang Parmar1 1Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA 2Sigma-Aldrich GmbH Industriestrasse 25 CH-9471 Buchs, Switzerland sigma-aldrich.com/analytical T413140 © 2013…
Key words
chirobiotic, chirobioticachiral, achiralpim, pimseparation, separationchiral, chiralpom, pomascentis, ascentisdiastereomers, diastereomersenantiomer, enantiomermode, modephase, phasereversed, reversedphenyl, phenyltag, tagcsps
Utilizing Enantiomeric Separations in Bioanalysis Craig R. Aurand, Hillel K. Brandes, David S. Bell, Wayne Way, and Carmen T. Santasania Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA www.sigma-aldrich.com T410094 Abstract Enantiomeric separations are often restricted in bioanalysis due to…
Key words
phospholipids, phospholipidsenantiomeric, enantiomericmacrocyclic, macrocycliccsps, cspslewis, lewisclenbuterol, clenbuterolhybridspe, hybridspemetoprolol, metoprololchiral, chiralglycopeptide, glycopeptidephases, phaseschirobiotic, chirobioticselectivity, selectivitysotalol, sotalolalprenolol
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