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High Throughput Non-Targeted Screening Using a Rapid Gradient Microbore UPLC Method and a Library of FDA-Approved Small Molecule Drugs

 

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A COMPARISON OF CONVENTIONAL AND RAPID GRADIENT MICROBORE LC CYCLIC™ ION MOBILITY MASS SPECTROMETRY FOR NON-TARGETED SCREENING OF BIOLOGICAL MATRICES 1 Michael McCullagh, 1Martin Palmer, 1Russell Mortishire-Smith, 1Emma Marsden-Edwards, 1Dale Cooper-Shepherd, 2Robert Plumb, 2Iggy Kass and 1Jeff Goshawk 1 Waters…
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Application Note Retention Time, Product Ion, and CCS Characterization of the Constituents of a FDA-Approved Small Molecule Pharmaceuticals Library Michael McCullagh, Jeff Goshawk, Russell J. Mortishire-Smith Waters Corporation Abstract A set of FDA-approved small molecule pharmaceuticals was used to produce…
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Application Note Extractables, Leachables, and Contact Materials: The Invaluable Benefit of Ion Mobility-Enhanced Mass Spectrometry Libraries Michael McCullagh, Russell J. Mortishire-Smith, Jeff Goshawk, Jane Cooper, Markus Obkircher, Hanspeter Sprecher, Rudolf Koehling, Matthias Nold, Jens Jacobsen, Rachel Sanig Waters Corporation, Merck…
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[ APPLICATION NOTE ] Unparalleled Multi-Factor Authentication Mass Spectrometry of Complex Natural Products Utilizing UPLC and Ion Mobility Michael McCullagh, Russell Mortishire-Smith, and Jeff Goshawk Waters Corporation, Wilmslow, UK APPLICATION BENEFITS ■ ■ Unique multi-factor authentication The application of LC-MS-based…
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