Intact Protein Analysis Using an Agilent 6550 Q-TOF Mass SpectrometerApplications | 2017 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Proteomics
Manufacturer
Agilent Technologies
Key words

 

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Application NotePharma & BiopharmaSensitive Native Mass Spectrometryof Macromolecules Using StandardFlow LC/MSAuthorDavid L. WongAgilent Technologies, Inc.AbstractNative mass spectrometry can be used for a variety of protein-based applications,such as protein-protein interaction, protein-ligand binding, protein complexstructures, protein folding and antibody-drug conjugates. Most of...
Key words
native, nativeprotein, proteincounts, countsintact, intactdeconvoluted, deconvolutedmyoglobin, myoglobinamu, amuapomyoglobin, apomyoglobincharge, chargemass, masscomplexes, complexesheme, hemeholomyoglobin, holomyoglobindenatured, denaturedtetramer
Precise Characterization of IntactMonoclonal Antibodies by theAgilent 6545XT AdvanceBio LC/Q-TOFApplication NoteAuthorIntroductionDavid L. WongMonoclonal antibodies (mAbs) are a very important class of biopharmaceuticalmolecules. As a protein drug, thorough characterization of the mAb is required in eachof the manufacturing steps. Intact mAb...
Key words
glcnac, glcnacintact, intactbioconfirm, bioconfirmdeconvoluted, deconvolutedmass, massdeconvolution, deconvolutionamu, amudar, darantibodies, antibodiesmab, mabglycoforms, glycoformscounts, countsmaxent, maxententropy, entropymonoclonal
LC/MS of Intact TherapeuticMonoclonal Antibodies UsingAgilent AdvanceBio RP-mAbApplication NoteBiologics and BiosimilarsAuthorIntroductionSuresh Babu C.V.Therapeutic proteins such as monoclonal antibodies (mAbs) are gaining muchattention in the biopharmaceutical industry. Post translational modifications duringthe mAb manufacturing process commonly result in microheterogeneity. Hence, it isimportant...
Key words
counts, countsmab, mabadvancebio, advancebiotherapeutic, therapeuticconjugated, conjugatedpmod, pmodagilent, agilentmabs, mabsintact, intactdrug, drugcharge, chargetemp, tempmass, massalgorithms, algorithmscolumns
Analysis of Monoclonal Antibody(mAb) Using Agilent 1290 InfinityLC System Coupled to Agilent 6530Accurate-Mass QuadrupoleTime-of-Flight (Q-TOF)Application NoteAuthorsAbstractRavindra Gudihal and Suresh Babu CVThis Application Note describes the use of an Agilent 1290 Infinity LC SystemAgilent Technologies India pvt. Ltd.coupled to an Agilent...
Key words
deconvoluted, deconvolutedcounts, countsamu, amupmod, pmodmass, massmab, mabintact, intactdeconvolution, deconvolutionmodeling, modelingalgorithm, algorithmmabs, mabsmasshunter, masshuntervoltage, voltagebioconfirm, bioconfirmpeak

Intact Protein Analysis Using an Agilent 6550 Q-TOF Mass SpectrometerApplications | 2017 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Proteomics
Manufacturer
Agilent Technologies
Key words

 

Similar PDF

Toggle
Application NotePharma & BiopharmaSensitive Native Mass Spectrometryof Macromolecules Using StandardFlow LC/MSAuthorDavid L. WongAgilent Technologies, Inc.AbstractNative mass spectrometry can be used for a variety of protein-based applications,such as protein-protein interaction, protein-ligand binding, protein complexstructures, protein folding and antibody-drug conjugates. Most of...
Key words
native, nativeprotein, proteincounts, countsintact, intactdeconvoluted, deconvolutedmyoglobin, myoglobinamu, amuapomyoglobin, apomyoglobincharge, chargemass, masscomplexes, complexesheme, hemeholomyoglobin, holomyoglobindenatured, denaturedtetramer
Precise Characterization of IntactMonoclonal Antibodies by theAgilent 6545XT AdvanceBio LC/Q-TOFApplication NoteAuthorIntroductionDavid L. WongMonoclonal antibodies (mAbs) are a very important class of biopharmaceuticalmolecules. As a protein drug, thorough characterization of the mAb is required in eachof the manufacturing steps. Intact mAb...
Key words
glcnac, glcnacintact, intactbioconfirm, bioconfirmdeconvoluted, deconvolutedmass, massdeconvolution, deconvolutionamu, amudar, darantibodies, antibodiesmab, mabglycoforms, glycoformscounts, countsmaxent, maxententropy, entropymonoclonal
LC/MS of Intact TherapeuticMonoclonal Antibodies UsingAgilent AdvanceBio RP-mAbApplication NoteBiologics and BiosimilarsAuthorIntroductionSuresh Babu C.V.Therapeutic proteins such as monoclonal antibodies (mAbs) are gaining muchattention in the biopharmaceutical industry. Post translational modifications duringthe mAb manufacturing process commonly result in microheterogeneity. Hence, it isimportant...
Key words
counts, countsmab, mabadvancebio, advancebiotherapeutic, therapeuticconjugated, conjugatedpmod, pmodagilent, agilentmabs, mabsintact, intactdrug, drugcharge, chargetemp, tempmass, massalgorithms, algorithmscolumns
Analysis of Monoclonal Antibody(mAb) Using Agilent 1290 InfinityLC System Coupled to Agilent 6530Accurate-Mass QuadrupoleTime-of-Flight (Q-TOF)Application NoteAuthorsAbstractRavindra Gudihal and Suresh Babu CVThis Application Note describes the use of an Agilent 1290 Infinity LC SystemAgilent Technologies India pvt. Ltd.coupled to an Agilent...
Key words
deconvoluted, deconvolutedcounts, countsamu, amupmod, pmodmass, massmab, mabintact, intactdeconvolution, deconvolutionmodeling, modelingalgorithm, algorithmmabs, mabsmasshunter, masshuntervoltage, voltagebioconfirm, bioconfirmpeak
 

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