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High-throughput MALDI-MS based read-out of high-density droplet microarrays facilitating next generation on-chip drug discovery

 

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MALDI Mass Spectrometry Application News Modified target surface to enhance performance during MALDI analysis Andreas Baumeister1, Maximilian Benz2, Wolfgang Sipos2 1 Shimadzu Europa GmbH, 2 Aquarray GmbH User Benefits u Higher number of samples on the target increases the throughput.…
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© Title Image - Analytik Jena Kinase inhibition screening by label-free mass spectrometry employing the MALDI PharmaPulse HTS solution Bruker´s MALDI PharmaPulse solution, integrating the rapifleX high-speed MALDI-TOF instrument with the dedicated MALDI PharmaPulse software suite, represents an emerging technology…
Key words
maldi, maldipharmapulse, pharmapulsekinase, kinaseabl, ablbruker, brukerhts, htssubstrate, substrateinhibitor, inhibitormpp, mppinhibition, inhibitionrapiflex, rapiflexenzyme, enzymetof, tofconversion, conversiontyrosine
Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate Novel Synthesis Screening workflow in MALDI PharmaPulse software that was developed for screening of synthetic chemical reactions is applied to screen a custom library…
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maldi, maldiscreening, screeningsynthesis, synthesisplate, platepharmapulse, pharmapulsetof, toffailed, failedultrahigh, ultrahighposition, positionruns, runsmolecule, moleculelibrary, librarynovel, novelphotoredox, photoredoxmodule
Profiling mammalian cell differentiation by MALDI-TOF MS: Developing a highly reproducible and robust sample preparation workflow In this application note, we present a universal workflow for mammalian cell MALDI-TOF MS analysis in order to distinguish between ground-state naïve and differentiating…
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maldi, malditof, tofrapiflex, rapiflexfreeze, freezelaser, laserpharmapulse, pharmapulsenaïve, naïvethaw, thawhts, htsassays, assayscell, cellcells, cellscellular, cellularthawing, thawingdhb
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