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Profiling mammalian cell differentiation by MALDI-TOF MS: Developing a highly reproducible and robust sample preparation workflow

 

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Label-free compound profiling in K562 leukemia cells by MALDI-TOF mass spectrometry using heme B as response marker Bruker’s very fast rapifleX MALDI PharmaPulse solution has been successfully used in pharmaceutical research for compound screening in various cell-free biochemical assays that…
Key words
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© Title Image - Analytik Jena Kinase inhibition screening by label-free mass spectrometry employing the MALDI PharmaPulse HTS solution Bruker´s MALDI PharmaPulse solution, integrating the rapifleX high-speed MALDI-TOF instrument with the dedicated MALDI PharmaPulse software suite, represents an emerging technology…
Key words
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Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate Novel Synthesis Screening workflow in MALDI PharmaPulse software that was developed for screening of synthetic chemical reactions is applied to screen a custom library…
Key words
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High-throughput MALDI-MS based read-out of high-density droplet microarrays facilitating next generation on-chip drug discovery On-chip miniaturized and parallelized solution-based synthesis of novel compound libraries followed by on-chip characterization and screening in droplet microarrays has the potential to accelerate the drug…
Key words
chip, chipaquarray, aquarraymaldi, maldidroplet, dropletdma, dmasynthesis, synthesischembios, chembiosrapiflex, rapiflexspot, spotpharmapulse, pharmapulsearrays, arraysmicroarray, microarraythroughput, throughputcharacterization, characterizationread
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