Analyzing Monoclonal Antibody (mAb) Fragments and Dimers Using Size Exclusion Chromatography (SEC)

Others | 2021 | Agilent TechnologiesInstrumentation
Consumables, LC columns, GPC/SEC
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
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Consumables Workflow Ordering Guide Analyzing Monoclonal Antibody (mAbs) and mAb-Derived Therapeutics Using Native SEC-MS The quantitation of aggregates is of particular concern for protein-based-therapies given their potential effect on efficacy and immunogenicity. Size exclusion chromatography (SEC) combined with UV detection…
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Consumables Workflow Ordering Guide Aggregate Analysis of Adeno-Associated Viruses and Virus-Like Particles in Biopharma by Liquid Chromatography Adeno-associated viruses (AAVs) and virus-like particles (VLPs) are emerging biotherapeutic molecules with exciting potential in the vaccine, cell, and gene therapy spaces. AAVs…
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Helpful ‘Hints’ for Protein SEC Success
2021|Agilent Technologies|Presentations
Helpful ‘Hints’ for Protein SEC Success Jean Lane Applications Engineer LC columns and consumables technical support May 27, 20201 Outline for Talk Getting started • SEC definition, common terminology, and why use it? • Considerations for selecting an SEC column…
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Consumables Workflow Ordering Guide Adeno-Associated Virus Identity Confirmation in Biopharma by LC/MS While adeno-associated viruses (AAVs) have their own unique set of critical quality attributes, many of the traditional assays used to monitor more established proteinbased therapeutics can still be…
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