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An Integrated Workflow for Automated Calculation of Antibody‑Drug Conjugate (ADC) Drug‑to-Antibody Ratio (DAR)

 

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Drug-to-Antibody Ratio (DAR) Calculation of Antibody-Drug Conjugates (ADCs) Using Automated Sample Preparation and Novel DAR Calculator Software Application Note Authors Introduction Jing Chen and Steve Murphy Antibody-drug conjugates (ADCs) are a new class of biotherapeutics that represent a rapidly growing…
Key words
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Application Note Pharma and Biopharma A streamlined drug-to-antibody ratio determination workflow for intact and deglycosylated antibody-drug conjugates Using the Agilent AssayMAP Bravo and Agilent 6545XT AdvanceBio accurate-mass quadrupole time-of-flight LC/MS system Authors Jerry Han, Zach Van Den Heuvel, and Steve…
Key words
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Agilent Biopharma Workflow Solutions
2016|Agilent Technologies|Brochures and specifications
Biopharma Workflow Solutions ACCELERATE ADC DAR CHARACTERIZATION WORKFLOW SOLUTIONS FOR ADC DAR ANALYSIS OVERVIEW The goal of drug discovery is to find drugs that have a wide differential between the effective dose and the dose where serious side effects are…
Key words
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Analysis of Antibody Drug Conjugate Through the Characterization of Drug Antibody Ratios Using an Agilent 1290 Infinity Binary LC System Coupled to an Agilent 6550 iFunnel Q-TOF Application Note Biopharma Authors Introduction Ravindra Gudihal and Jing Chen Antibody drug conjugates…
Key words
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