A streamlined drug-to-antibody ratio determination workflow for intact and deglycosylated antibody-drug conjugates
Applications | 2019 | Agilent TechnologiesInstrumentation
Sample Preparation, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsdeglycosylation, affinity, assaymap, adc, dar, cartridges, adcs, cartridge, streptavidin, purified, serum, antibody, purification, were, sulfo, buffer, nhs, immobilization, antigen, biotin, bravo, deconvoluted, from, drug, biotinylated, rat, intact, deglycosylated, using, auc, excess, pngase, spectrum, agilent, analyzed, workflow, mass, eics, vivo, loaded, conjugates, hepes, molar, chase, flight, sample, ligand, masshunter, equilibrate, flow
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