LCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike

Determination of Drug-to-Antibody Ratio for Antibody-Drug Conjugates Purified from Serum

Applications | 2016 | Agilent TechnologiesInstrumentation
Sample Preparation, Software, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Clinical Research
Manufacturer
Agilent Technologies
Key words
Downloadable PDF for viewing
 

Similar PDF

Toggle
Application Note Pharma and Biopharma A streamlined drug-to-antibody ratio determination workflow for intact and deglycosylated antibody-drug conjugates Using the Agilent AssayMAP Bravo and Agilent 6545XT AdvanceBio accurate-mass quadrupole time-of-flight LC/MS system Authors Jerry Han, Zach Van Den Heuvel, and Steve…
Key words
deglycosylation, deglycosylationaffinity, affinityassaymap, assaymapadc, adcdar, darcartridges, cartridgesadcs, adcscartridge, cartridgestreptavidin, streptavidinpurified, purifiedserum, serumantibody, antibodywere, werepurification, purificationsulfo
Application Note Biotherapeutics & Biosimilars Drug to Antibody Ratio Analysis of Brentuximab Vedotin in Monkey Plasma Antibody drug conjugate analysis under native conditions using Agilent AdvanceBio 6545XT LC/Q-TOF systems Authors Xi Qiu and Kenda LJ Evans Agilent Technologies, Inc. Andrea…
Key words
brentuximab, brentuximabdar, darmonkey, monkeylba, lbaadc, adcamu, amudeconvoluted, deconvoluteddrug, drugcounts, countsadcs, adcsnative, nativeantibody, antibodyassaymap, assaymapagilent, agilentbravo
An Integrated Workflow for Automated Calculation of Antibody‑Drug Conjugate (ADC) Drug‑to-Antibody Ratio (DAR) Using Automated Sample Preparation, Agilent MassHunter Walkup, and Agilent MassHunter BioConfirm DAR Calculator Software Application Note Biotherapeutics and Biosimilars Authors Abstract David L. Wong, Tanner Stevenson, and…
Key words
dar, daradc, adcdeconvoluted, deconvoluteddeglycosylated, deglycosylatedintact, intactreduced, reducedadcs, adcsantibody, antibodybioconfirm, bioconfirmdrug, drugassaymap, assaymapglycosylated, glycosylatedbravo, bravocounts, countscalculator
Drug-to-Antibody Ratio (DAR) Calculation of Antibody-Drug Conjugates (ADCs) Using Automated Sample Preparation and Novel DAR Calculator Software Application Note Authors Introduction Jing Chen and Steve Murphy Antibody-drug conjugates (ADCs) are a new class of biotherapeutics that represent a rapidly growing…
Key words
dar, dardeconvoluted, deconvolutedadcs, adcscounts, countsglycosylated, glycosylateddeglycosylated, deglycosylatedgiven, givenassaymap, assaymapspectra, spectrachain, chainbioconfirm, bioconfirmintact, intactmass, massamu, amubravo
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike