Reliable quantitation of 11 nitrosamine impurities in metformin drug products using Orbitrap Exploris 120 mass spectrometry
Applications | 2021 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordsmetformin, positive, nmpa, ndma, nitrosamine, ndba, nmba, nmea, npip, npyr, neipa, ndipa, ndpa, ndea, drug, nitrosamines, minutes, impurities, counts, hesi, tsim, quantitation, hram, standards, apci, were, cambridge, mode, method, products, resolution, ppb, dmf, regulatory, lod, loq, wash, ionization, tablets, isotopes, targeted, ion, metfformin, chromatographic, mobile, negative, neat, reliable, nitrosomethylphenylamine, atmospheric
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