Biotage Extrahera (Release Notes)

Importance of the topic

Automated sample preparation is a critical component in modern analytical workflows. It ensures consistency, reduces manual labor, and enhances throughput across various application areas such as environmental analysis food safety pharmaceutical research and quality control laboratories.

Objectives and overview

This summary outlines the major software enhancements and new features introduced in Biotage Extrahera release versions from 1.5.1 through 2.0.1. It highlights improved method flexibility compliance tools and system reliability aimed at meeting demanding laboratory requirements.

Methodology and instrumentation

Instrument used

• Biotage Extrahera automated sample preparation system

Key software features

• Method definition modules for SPE SLE Filtration and Filtration plus
• User interface updates including network backup maintenance and remote monitoring
• GLP software license for user accounts audit trail and method locking
• Sample batch worklist import and dynamic reporting
• Clog detection and automated clearing routines

Accessories and consumables

• Column racks in 96 48 and 24 formats
• New SLE plus and FILTER plus extraction media
• Wide bore pipette tips and solvent racks for volatile solvents

Key results and discussion

Version 2.0.1 introduced up to 100 rinse cycles per SPE method extended conditional repeats and improved parameter naming for clarity. Version 2.0 added the GLP license enabling secure login user roles audit trails and protected PDF reports. Individual sample runs for small batches and new Hydro DME plus dual mode extraction expanded method capabilities. Support for 48 position racks and locking of solvents to reservoirs increased operational flexibility. Email notifications network share integration and barcode scanner support enhanced workflow monitoring and data management. Earlier 1.5 releases delivered new Filtration and Filtration plus methods adjustable pressure gradients zero volume pipetting sample pretreatment mixing and aspirate post dispense options.

Benefits and practical applications

• Enhanced reproducibility through method locking audit trails and system alarms
• Compliance readiness via secure user roles protected output and calibration reminders
• Improved throughput enabled by sample pipette tip reuse rinse cycles and individual sample runs
• Flexible solvent handling including volatile solvent management and dynamic reservoir locking
• Remote access and notifications facilitate unattended or off site monitoring

Future trends and opportunities

Next generation systems will likely integrate deeper connectivity with laboratory information management systems cloud based data analysis and machine learning algorithms for predictive maintenance and automated method optimization. Expanded sensor technology will further enhance clog detection and process control. Development of green solvents and sustainable consumables may reduce environmental impact.

Conclusion

Biotage Extrahera software evolution delivers powerful new tools for automated sample preparation addressing method versatility compliance and operational efficiency. The continuous addition of features such as GLP governance intelligent error handling and expanded method support positions the system as a flexible platform for diverse analytical needs.

Reference

Biotage Extrahera Release Notes Versions 1.5.1 to 2.0.1 Biotage AB 2020