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Use of Charged Aerosol Detection as an Orthogonal Quantification Technique for Drug Metabolites in Safety Testing (MIST)

 

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Quantification of Drug Metabolites in Early-Stage Drug Discovery Testing Christopher Crafts, Bruce Bailey, John Waraska, Ian Acworth Thermo Fisher Scientific, Chelmsford, MA, USA Overview Methods Purpose: The use of a high efficiency UHPLC column and charged aerosol detection were evaluated…
Key words
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Improving the Quantitation of Unknown Impurity Analysis Using Dual-Gradient HPLC with Charged Aerosol Detection Christopher Crafts, Bruce Bailey, Marc Plante, John Waraska, and Ian Acworth ESA—A Dionex Company, Chelmsford, MA USA ABSTRACT INTRODUCTION Quantification of substances such as drug impurities…
Key words
inverse, inversegradient, gradientaerosol, aerosolcad, cadresponse, responsecurve, curvecharged, chargedcompounds, compoundshplc, hplcunknown, unknownofimpurity, ofimpurityprogestrone, progestronetheofquantitation, theofquantitationusingofdual, usingofdualacetominophen
Bruce Bailey, Ph. D. Thermo Fisher Scientific, Chelmsford, MA, USA Ap plica t ion Note 1 1 26 Metoprolol and Select Impurities Analysis Using a Hydrophilic Interaction Chromatography Method with Combined UV and Charged Aerosol Detection Key Words Vanquish UHPLC…
Key words
metoprolol, metoprololaerosol, aerosolcharged, chargedimp, impimpurity, impuritypolynomial, polynomialdetector, detectorcad, cadmix, miximpurities, impuritieschromophore, chromophorediode, diodevanquish, vanquishwell, wellarray
HPLC - UV-Vis absorption and charged aerosol detection
2020|Thermo Fisher Scientific|Guides
Table of contents Summary Overview: Dietary supplements and botanical natural products Overview: Global market Measurement and analysis Instrumentation Sample preparation Separation Detection Authentication of supplements LC that takes your productivity to new heights Application examples Substances A-C Substances D-G Substances…
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substances, substancessupplements, supplementsglossary, glossarybotanical, botanicaldietary, dietaryauthentication, authenticationnatural, naturalliterature, literatureaerosol, aerosolexamples, examplescontents, contentscharged, chargeddetection, detectionanon, anonhplc
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