Use of Charged Aerosol Detection as an Orthogonal Quantification Technique for Drug Metabolites in Safety Testing (MIST) | LabRulez LCMS_EN
 

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Bruce Bailey, Ph. D.Thermo Fisher Scientific, Chelmsford, MA, USAAp plica t ion Note 1 1 26Metoprolol and Select ImpuritiesAnalysis Using a Hydrophilic InteractionChromatography Method with CombinedUV and Charged Aerosol DetectionKey WordsVanquish UHPLC System, Metoprolol, Metoprolol EP Impurity A, MetoprololEP Impurity...
Key words
metoprolol, metoprololaerosol, aerosolcharged, chargedimp, impimpurity, impuritypolynomial, polynomialdetector, detectorcad, cadimpurities, impuritiesmix, mixchromophore, chromophorevanquish, vanquishdiode, diodewell, wellarray
HPLC - UV-Vis absorption and charged aerosol detection
2020|Thermo Fischer Scientific|Guides
Table of contentsSummaryOverview:Dietary supplements andbotanical natural productsOverview: Global marketMeasurement and analysisInstrumentationSample preparationSeparationDetectionAuthentication ofsupplementsLC that takes yourproductivity tonew heightsApplication examplesSubstances A-CSubstances D-GSubstances H-MSubstances N-TSubstances U-ZLiteratureGlossaryHPLC - UV-Vis absorption andcharged aerosol detectionDietary supplements and botanical natural products applications notebookComplex samples, powerful chromatographic...
Key words
substances, substancessupplements, supplementsglossary, glossarybotanical, botanicaldietary, dietaryauthentication, authenticationnatural, naturalaerosol, aerosolliterature, literatureexamples, examplescontents, contentscharged, chargeddetection, detectionmeasurement, measurementsummary
Improving the Quantitation of Unknown Impurity AnalysisUsing Dual-Gradient HPLC with Charged Aerosol DetectionChristopher Crafts, Bruce Bailey, Marc Plante, John Waraska, and Ian AcworthESA—A Dionex Company, Chelmsford, MA USAABSTRACTINTRODUCTIONQuantification of substances such as drug impurities or library compoundswhen pure standards are...
Key words
inverse, inversegradient, gradientaerosol, aerosolcad, cadcurve, curveresponse, responsecharged, chargedhplc, hplccompounds, compoundsunknown, unknownofimpurity, ofimpurityprogestrone, progestronetheofquantitation, theofquantitationusingofdual, usingofdualacetominophen
Quantification of Drug Metabolites inEarly-Stage Drug Discovery TestingChristopher Crafts, Bruce Bailey, John Waraska, Ian AcworthThermo Fisher Scientific, Chelmsford, MA, USA OverviewMethodsPurpose: The use of a high efficiency UHPLC column and charged aerosol detectionwere evaluated for the quantification of drug metabolites.Sample PreparationSamples...
Key words
charged, chargedaerosol, aerosolcad, caddrug, drugacetaminophen, acetaminophenmetabolites, metabolitesresponse, responseinverse, inversedetection, detectionstage, stagetechnique, techniqueuniversal, universalglutathione, glutathionemicrosome, microsomeapi
 

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Bruce Bailey, Ph. D.Thermo Fisher Scientific, Chelmsford, MA, USAAp plica t ion Note 1 1 26Metoprolol and Select ImpuritiesAnalysis Using a Hydrophilic InteractionChromatography Method with CombinedUV and Charged Aerosol DetectionKey WordsVanquish UHPLC System, Metoprolol, Metoprolol EP Impurity A, MetoprololEP Impurity...
Key words
metoprolol, metoprololaerosol, aerosolcharged, chargedimp, impimpurity, impuritypolynomial, polynomialdetector, detectorcad, cadimpurities, impuritiesmix, mixchromophore, chromophorevanquish, vanquishdiode, diodewell, wellarray
HPLC - UV-Vis absorption and charged aerosol detection
2020|Thermo Fischer Scientific|Guides
Table of contentsSummaryOverview:Dietary supplements andbotanical natural productsOverview: Global marketMeasurement and analysisInstrumentationSample preparationSeparationDetectionAuthentication ofsupplementsLC that takes yourproductivity tonew heightsApplication examplesSubstances A-CSubstances D-GSubstances H-MSubstances N-TSubstances U-ZLiteratureGlossaryHPLC - UV-Vis absorption andcharged aerosol detectionDietary supplements and botanical natural products applications notebookComplex samples, powerful chromatographic...
Key words
substances, substancessupplements, supplementsglossary, glossarybotanical, botanicaldietary, dietaryauthentication, authenticationnatural, naturalaerosol, aerosolliterature, literatureexamples, examplescontents, contentscharged, chargeddetection, detectionmeasurement, measurementsummary
Improving the Quantitation of Unknown Impurity AnalysisUsing Dual-Gradient HPLC with Charged Aerosol DetectionChristopher Crafts, Bruce Bailey, Marc Plante, John Waraska, and Ian AcworthESA—A Dionex Company, Chelmsford, MA USAABSTRACTINTRODUCTIONQuantification of substances such as drug impurities or library compoundswhen pure standards are...
Key words
inverse, inversegradient, gradientaerosol, aerosolcad, cadcurve, curveresponse, responsecharged, chargedhplc, hplccompounds, compoundsunknown, unknownofimpurity, ofimpurityprogestrone, progestronetheofquantitation, theofquantitationusingofdual, usingofdualacetominophen
Quantification of Drug Metabolites inEarly-Stage Drug Discovery TestingChristopher Crafts, Bruce Bailey, John Waraska, Ian AcworthThermo Fisher Scientific, Chelmsford, MA, USA OverviewMethodsPurpose: The use of a high efficiency UHPLC column and charged aerosol detectionwere evaluated for the quantification of drug metabolites.Sample PreparationSamples...
Key words
charged, chargedaerosol, aerosolcad, caddrug, drugacetaminophen, acetaminophenmetabolites, metabolitesresponse, responseinverse, inversedetection, detectionstage, stagetechnique, techniqueuniversal, universalglutathione, glutathionemicrosome, microsomeapi
 

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