Use of Charged Aerosol Detection as an Orthogonal Quantification Technique for Drug Metabolites in Safety Testing (MIST)Posters | 2011 | Thermo Fischer ScientificInstrumentationHPLCIndustriesClinical ResearchManufacturerThermo Fischer ScientificKey wordscad, buspirone, mist, metabolites, aerosol, drug, erythromycin, metabolite, metabolitesin, orthogona, squibb, charged, myers, testing, detection, safety, work, quantification, ltq, vitro, technique, mau, discussed, optimization, nano, bristoyl, dscovery, eyr, cases, hrms, proteomics, cai, emi, response, bristol, america, sufficient, orbitrap, presented, provide, interpretations, overestimation, chromophoric, major, hong, needed, electrometer, examines, here, meet
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Metoprolol and Select Impurities Analysis Using a Hydrophilic Interaction Chromatography Method with Combined UV and Charged Aerosol Detection
2016|Thermo Fischer Scientific|Applications
Bruce Bailey, Ph. D.Thermo Fisher Scientific, Chelmsford, MA, USAAp plica t ion Note 1 1 26Metoprolol and Select ImpuritiesAnalysis Using a Hydrophilic InteractionChromatography Method with CombinedUV and Charged Aerosol DetectionKey WordsVanquish UHPLC System, Metoprolol, Metoprolol EP Impurity A, MetoprololEP Impurity...
Key words
metoprolol, metoprololaerosol, aerosolcharged, chargedimp, impimpurity, impuritypolynomial, polynomialdetector, detectorcad, cadimpurities, impuritiesmix, mixchromophore, chromophorevanquish, vanquishdiode, diodewell, wellarray
Table of contentsSummaryOverview:Dietary supplements andbotanical natural productsOverview: Global marketMeasurement and analysisInstrumentationSample preparationSeparationDetectionAuthentication ofsupplementsLC that takes yourproductivity tonew heightsApplication examplesSubstances A-CSubstances D-GSubstances H-MSubstances N-TSubstances U-ZLiteratureGlossaryHPLC - UV-Vis absorption andcharged aerosol detectionDietary supplements and botanical natural products applications notebookComplex samples, powerful chromatographic...
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EAS: Improving the Quantitation of Unknown Impurity Analysis Using Dual-Gradient HPLC with Charged Aerosol Detection
2010|Thermo Fischer Scientific|Posters
Improving the Quantitation of Unknown Impurity AnalysisUsing Dual-Gradient HPLC with Charged Aerosol DetectionChristopher Crafts, Bruce Bailey, Marc Plante, John Waraska, and Ian AcworthESA—A Dionex Company, Chelmsford, MA USAABSTRACTINTRODUCTIONQuantification of substances such as drug impurities or library compoundswhen pure standards are...
Key words
inverse, inversegradient, gradientaerosol, aerosolcad, cadcurve, curveresponse, responsecharged, chargedhplc, hplccompounds, compoundsunknown, unknownofimpurity, ofimpurityprogestrone, progestronetheofquantitation, theofquantitationusingofdual, usingofdualacetominophen
Quantification of Drug Metabolites in Early-Stage Drug Discovery Testing
2016|Thermo Fischer Scientific|Posters
Quantification of Drug Metabolites inEarly-Stage Drug Discovery TestingChristopher Crafts, Bruce Bailey, John Waraska, Ian AcworthThermo Fisher Scientific, Chelmsford, MA, USA OverviewMethodsPurpose: The use of a high efficiency UHPLC column and charged aerosol detectionwere evaluated for the quantification of drug metabolites.Sample PreparationSamples...
Key words
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