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Quantification of Drug Metabolites in Early-Stage Drug Discovery Testing

 

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Use of Charged Aerosol Detection as an Orthogonal Quantification Technique for Drug Metabolites in Safety Testing (MIST) Christopher Crafts, Bruce Bailey, Marc Plante, John Waraska, Paul Gamache, and Ian Acworth ESA—A Dionex Company, Chelmsford, MA, USA Abstract INTRODUCTION The publication…
Key words
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Improving the Quantitation of Unknown Impurity Analysis Using Dual-Gradient HPLC with Charged Aerosol Detection Christopher Crafts, Bruce Bailey, Marc Plante, John Waraska, and Ian Acworth ESA—A Dionex Company, Chelmsford, MA USA ABSTRACT INTRODUCTION Quantification of substances such as drug impurities…
Key words
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Thermo Scientific Charged Aerosol Detectors
2018|Thermo Fisher Scientific|Brochures and specifications
Discover what you’re missing Thermo Scientific Charged Aerosol Detectors Hidden peaks revealed The analyte detection challenge No single liquid chromatography (LC) detector delivers ideal results. Often, one analyte responds more strongly than another, or may not respond at all. What…
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TECHNICAL NOTE 72806 Charged aerosol detection - factors affecting uniform analyte response Authors Michael Menz1, Benjamin Eggart1, Katherine Lovejoy1, Ian Acworth2, Paul Gamache2, Frank Steiner1 Thermo Fisher Scientific, Germering, Germany 1 ²Thermo Fisher Scientific, Chelmsford, MA, USA Table of Contents…
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