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ASMS: Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos Tribrid Mass Spectrometer

Posters | 2016 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Pharma & Biopharma
Manufacturer
Thermo Fisher Scientific
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Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer Jie Qian,1 Keith A. Waddell, 2 Zhiqi Hao2 1 Thermo Fisher Scientific, Somerset, NJ, 2Thermo Fisher Scientific San Jose, CA Overview Results Purpose:…
Key words
mab, mababundan, abundanrelative, relativeetd, etdmiddle, middleabundance, abundancence, nceorbitrap, orbitrapdown, downdissociation, dissociationndance, ndancemass, massabun, abunintact, intactfusion
MSUM: NEW on Thermo Scientific Orbitrap Fusion Lumos Tribrid MS
2016|Thermo Fisher Scientific|Presentations
NEW on Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ MS Stephane Houel, Ph.D. BioPharma Vertical Marketing The world leader in serving science NEW On Thermo Scientific Orbitrap Fusion Lumos MS in 2017 ADVANCED PEAK DETERMINATION ALGORITHM RESULTS IN SIGNIFICANT IMPROVEMENT IN…
Key words
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Native Top-Down Analysis of Intact Antibodies using Multiple Dissociation Techniques on a Tribrid Quadrupole Orbitrap Linear Ion Trap Mass Spectrometer Eugen Damoc1, Kristina Srzentić2, Romain Huguet3, Graeme McAlister3, Christopher Mullen3, Philip M Remes3, Jesse D Canterbury3, Mike Senko3, and Vlad…
Key words
abundance, abundancerelative, relativeorbitrap, orbitrapstatuslog, statuslogqualbrowser, qualbrowserintact, intacttop, topdown, downmass, massnative, nativeeclipse, eclipsehmrn, hmrnherceptin, herceptinantibodies, antibodiestribrid
A Complete Workflow Solution for Intact Monoclonal Antibody Characterization Using a New High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS Zhiqi Hao,1 Yi Zhang,1 David Horn,1 Seema Sharma,1 Shiaw-Lin Wu, 2 Irene Ae-Ning Lin, 3 Yi-Hsuan Pan, 3 Ya-Fen Yang, 3 and Andreas F.…
Key words
mab, mababundance, abundanceintact, intactrelative, relativeexactive, exactivehcd, hcdspectrum, spectrumfile, fileorbitrap, orbitrapenvelope, envelopemass, masscharge, chargedeconvolution, deconvolutiondown, downantibody
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