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Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer

Posters | 2014 | Thermo Fisher Scientific | ASMSInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Pharma & Biopharma
Manufacturer
Thermo Fisher Scientific
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Poster Note 64778 Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos™ Tribrid Mass Spectrometer Seema Sharma, Stephane Houel, Christopher Mullen, Chad Weisbrod, Romain Huguet, John Syka, Dave Horn, Jonathan Josephs, Jae Schwartz, Vlad Zabrouskov Thermo Fisher Scientific, San…
Key words
abundance, abundancefragmentation, fragmentationantibody, antibodyintact, intactetd, etdrelative, relativemab, mabtop, topdown, downheavy, heavymonoclonal, monoclonaluvpd, uvpddeglycosylated, deglycosylatedpulses, pulsessequence
APPLICATION NOTE 73885 Complete characterization of monoclonal antibodies under native and denaturing conditions Kristina Srzentić1, Eugen Damoc2, Kai Scheffler3, Tom Buchanan4, Krisztina Radi4, Jennifer Sutton1 Thermo Fisher Scientific, 1 Cambridge, Massachusetts, US 2 Bremen, Germany 3 Germering, Germany 4 Hemel…
Key words
intact, intacttrastuzumab, trastuzumabnative, nativemass, masshcd, hcdmab, mabsubunit, subunitdown, downdeconvolution, deconvolutionthermo, thermoscientific, scientificsubunits, subunitspeptide, peptidemiddle, middleheavy
MSUM: NEW on Thermo Scientific Orbitrap Fusion Lumos Tribrid MS
2016|Thermo Fisher Scientific|Presentations
NEW on Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ MS Stephane Houel, Ph.D. BioPharma Vertical Marketing The world leader in serving science NEW On Thermo Scientific Orbitrap Fusion Lumos MS in 2017 ADVANCED PEAK DETERMINATION ALGORITHM RESULTS IN SIGNIFICANT IMPROVEMENT IN…
Key words
uvpd, uvpdapd, apdcoverage, coverageunique, uniqueetd, etdexisting, existingnew, newlumos, lumossystems, systemsoptional, optionalpeptide, peptidetrap, trapproteomics, proteomicsfragmentation, fragmentationdependent
Go beyond in biopharmaceutical characterization
2020|Thermo Fisher Scientific|Technical notes
65653 WHITE PAPER Go beyond in biopharmaceutical characterization Unprecedented insights into the most advanced biotherapeutics are revealed by utilizing the pioneering technology and software developments incorporated into the Thermo Scientific™ Orbitrap Eclipse™ Tribrid™ mass spectrometer. Abstract The pioneering technology and…
Key words
ptcr, ptcrmass, massion, ionorbitrap, orbitraptribrid, tribrideclipse, eclipseproduct, productcharacterization, characterizationetd, etdcharge, chargenative, nativedown, downions, ionsresulting, resultingstate
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