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LipidQuan™: A Robust LC-MS/MS Methodology for Rapidly Profiling the Lipidome of Liver Tissue Following Metabolism of the Drug Gefitinib

 

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LIPIDOMIC AND DESI IMAGING STUDY OF MOUSE LIVER DOSED WITH A TYROSINE KINASE INHIBITING DRUG Nyasha Munjoma 1 , Giorgis Isaac 2 , Mark Towers 1 , Emmanuelle Claude 1 , Ian D Wilson 3 , Lee A. Gethings 1…
Key words
desi, desiimaging, imaginguntargeted, untargetedgefitinib, gefitiniblipidomics, lipidomicstissue, tissueccs, ccslipid, lipidkinase, kinasegefitnib, gefitnibpremier, premiertreated, treatedstatistical, statisticalomics, omicstyrosine
English Hong Kong | Application Note A Rapid, Workflow Driven Approach to Discovery Lipidomics Using Ion Mobility DIA UPLC/MS and Lipostar™ Nyasha Munjoma, Lee A. Gethings, Robert S. Plumb, Graham Mullard, Paolo Tiberi, Laura Goracci Waters Corporation, University of Perugia,…
Key words
lipostar, lipostarliver, liverlipidome, lipidomequality, qualitylipidomics, lipidomicsdia, diauplc, uplcinformatics, informaticsmultivariate, multivariateevotec, evotecassurance, assurancemetabolomics, metabolomicsmobility, mobilitymetasite, metasitetwims
[ APPLICATION NOTE ] LipidQuan: Quantifying the Lipidome of Transgenic Mice Tissue Extracts, a Rapid and Comprehensive Targeted Approach Nyasha Munjoma, 1 Giorgis Isaac, 1 Lee A. Gethings,1 Caitlyn Da Costa,1 Robert S. Plumb,1 Amanda D.V. MacCannell, 2 and Lee…
Key words
trangenic, trangeniclipidquan, lipidquanmouse, mouseconc, conclipids, lipidstargetlynx, targetlynxapplication, applicationallowed, alloweduplc, uplcnote, noteacquity, acquitylpe, lpestd, stdmurine, murinelpc
[ APPLICATION NOTE ] A Rapid UPLC-MS/MS Discovery Bioanalytical Method for the Quantification of Gefitinib and Four of Its Major Metabolites in Mouse Plasma Billy J. Molloy, Ian D. Wilson, and Robert S. Plumb Waters Corporation, Milford, MA, USA APPLICATION…
Key words
gefitinib, gefitinibiressa, iressadesmethyl, desmethyldiscovery, discoverybioanalytical, bioanalyticaluplc, uplcmetabolites, metabolitesrapid, rapidmetabolite, metabolitemajor, majorfour, fourpharmacokinetics, pharmacokineticsdose, dosedrug, drugepidermal
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