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Automating Rapid High-Throughput LC-MS mAb Subunit Screening of Microbioreactor Cell Culture Samples

 

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[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…
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Automating Rapid High-throughput mAb Attribute Screening of Microbioreactor Cell Culture Media Samples Alireza Aghayee1, Yamin Htet2, Lindsay Morrison2, Stephan M. Koza2, Ying Qing Yu2 1 Pall Corporation, Westborough, MA, USA; 2Waters Corporation, Milford, MA, USA INTRODUCTION RESULTS AND DISCUSSION …
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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
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AUTOMATING SUBUNIT MAB ATTRIBUTE SCREENING FOR IN-PROCESS MONITORING OF AN AUTOMATED HIGH-THROUGHPUT MULTI-PARALLEL BIOREACTOR Nick Pittman1; Patrick Boyce1; Caitlin Hanna2; Samantha Ippoliti2; Yun W Alelyunas2; Charles Prochaska3; Clint Kukla3; Guillaume Bechade1; Magnus Wetterhall1; Mark Wrona2; Stephan M Koza2; Ying Qing…
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