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Comprehensive Biosimilar Comparability Assessment via Intact and Subunit RP-MS and IEX-UV-MS Using the Xevo™ G3 QTof System

 

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A Robust Workflow for Biosimilar Comparability Assessment via Intact and Subunit RPLC-MS and Native IEX-MS with the Xevo G3 QTof MS Platform Ippoliti1; Cornwell2; Reid2; Yu1; Harry2; Charge Variant Analysis (IEX-MS) Berger1; Samantha Owen Lisa Ying Qing Emma Scott 1Waters…
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MP012 A Robust Workflow for Biosimilar Comparability Assessment via Intact and Subunit RPLC-MS and Native IEX-MS with a Prototype Benchtop QTOF Charge Variant Analysis (IEX-MS) Samantha Ippoliti1; Owen Cornwell2; Lisa Reid2; Ying Qing Yu1; Emma Harry2; Scott Berger1; 1Waters Corporation,…
Key words
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Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…
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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
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