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A Robust Workflow for Biosimilar Comparability Assessment via Intact and Subunit RPLC-MS and Native IEX-MS with the Xevo G3 QTof MS Platform

 

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MP012 A Robust Workflow for Biosimilar Comparability Assessment via Intact and Subunit RPLC-MS and Native IEX-MS with a Prototype Benchtop QTOF Charge Variant Analysis (IEX-MS) Samantha Ippoliti1; Owen Cornwell2; Lisa Reid2; Ying Qing Yu1; Emma Harry2; Scott Berger1; 1Waters Corporation,…
Key words
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Application Note Comprehensive Biosimilar Comparability Assessment via Intact and Subunit RP-MS and IEX-UV-MS Using the Xevo™ G3 QTof System Samantha Ippoliti, Owen Cornwell, Lisa Reid, Ying Qing Yu, Emma Harry, Mark Towers Waters Corporation Abstract With the increasing prevalence of…
Key words
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Application Note Applying Peptide Mapping and MultiAttribute Method (MAM) Workflow for Biosimilar mAb Drug Products Comparison on the Xevo™ G3 QTof Platform Kellen DeLaney, Samantha Ippoliti, Lisa Reid, Owen Cornwell, Ying Qing Yu, Emma Harry, Mark Towers Waters Corporation Abstract…
Key words
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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
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