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Adeno-Associated Virus Identity Confirmation in Biopharma by LC/MS

 

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Application Note LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity Author Brian Liau Agilent Technologies, Inc. Introduction Adeno-associated viruses (AAVs) are a promising new class of biotherapeutic capable of treating a host of rare and…
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Application Note Pharma & Biopharma Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies, Inc., Lexington, MA, USA Roy Hegedus and Norman Garceau Lake Pharma, Worcester, MA, USA…
Key words
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Host Cell Protein Analysis by RP-LC/MS
2023|Agilent Technologies|Guides
Consumables Workflow Ordering Guide Host Cell Protein Analysis by RP-LC/MS Unlike small molecules and oligos, mAbs and other protein-based therapeutics, including adeno-associated virus (AAV) capsids are engineered and produced using a cell line. These cell lines include CHO (Chinese Hamster…
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Poster Reprint ASMS 2020 ThP 466 Purity and Identity Characterization of AdenoAssociated Virus Capsid Particles by Intact and BottomUp Based Liquid Chromatography-Mass Spectrometry Methods Wendi A. Hale1, Dominique Garceau2, Tristan Cano2, Caitlin Jaeger2, Roy Hegedus2, William Hermans2, Norman Garceau2, Christopher…
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capsid, capsidviral, viralspectrum, spectrumaavs, aavsswarm, swarmcqas, cqasintact, intacttherapy, therapyptms, ptmsgene, genepeptide, peptideproteins, proteinsautotune, autotunetranslational, translationalprotein
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