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Extraction of N-terminally Blocked Proteins from Electrophoresis Gels and Sequence Analysis Using a Benchtop MALDI-TOF Mass Spectrometer

 

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Next-generation MALDI top-down sequencing of protein biotherapeutics – expanding the scope of timsTOF technology Next-generation MALDI top-down sequencing (MALDI-TDS) improves top-down sequence analysis of biopharmaceutical proteins, as demonstrated in this note for adalimumab subunits, recombinant SARS-CoV-2 S-glycoprotein RBD expression products,…
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maldi, malditds, tdsterminal, terminalisd, isdtims, timsnext, nextgeneration, generationsequence, sequencetimstof, timstofsequencing, sequencingprotein, proteinfragments, fragmentssubunits, subunitsflex, flexdown
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culture, cultureindex, indexpharmacokinetics, pharmacokineticscell, cellmouse, mousecharacterization, characterizationothers, otherspurification, purificationcontrol, controlquality, qualitymeasurement, measurementoptimization, optimizationprinciple, principleanalysis, analysisoperating
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culture, cultureindex, indexpharmacokinetics, pharmacokineticscell, cellmouse, mousecharacterization, characterizationothers, otherspurification, purificationcontrol, controlquality, qualitymeasurement, measurementoptimization, optimizationprinciple, principleanalysis, analysisoperating
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excision, excisionunprotected, unprotecteddds, ddscharacteristic, characteristicindex, indexoligomer, oligomerpharmacokinetics, pharmacokineticsquality, qualityoligonucleotide, oligonucleotidecontrol, controlsynthesis, synthesispurification, purificationmodification, modificationtorast, torastanalysis
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