SureSTART collection for every HPLC/UHPLC

Significance of the topic

In advanced chromatographic analysis, consistent sample handling is crucial.
SureSTART consumables support sample integrity, minimize adsorption and ensure reproducible data across HPLC, UHPLC and mass spectrometry platforms.

Objectives and overview

This summary outlines Thermo Scientific SureSTART vials, caps, inserts and well plates, structured into three performance tiers to match analytical requirements and budget constraints.
The product range aims to deliver quality, compatibility and cost efficiency in routine and high-performance workflows.

Used instrumentation

• High-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC) autosamplers
• Mass spectrometry systems (single, triple quadrupole, Orbitrap)
• Charged aerosol detection (CAD)

Methodology and product design

The SureSTART line is divided into three distinct levels:

• Level 1 (Everyday analysis) – cost-optimized, chromatography-approved vials and caps for standard detection techniques (UV/Vis, PDA, RI, ELSD, FLD).
• Level 2 (High-throughput analysis) – low metal content, minimal extractables/leachables, advanced AVCS and SureStop closure technologies for regulated environments.
• Level 3 (High performance) – clean-room packaging, GOLD-Grade glass, high-recovery inserts, ultra-low adsorption for trace-level sensitivity and HRAM accuracy.

Main features and discussion

• Chromatography compatibility across HPLC/UHPLC instruments.
• Advanced closure systems (AVCS, SureStop) to secure seals and prevent leaks.
• GOLD-Grade glass and specialized inserts to reduce sample loss at trace levels.
• Five vial formats and multiple cap/septa options to cover diverse applications.
• Well plates and mats designed for high-throughput microplate workflows.

Benefits and practical applications

• Assured quality controls and stringent testing to meet regulatory standards.
• Cost savings through tiered performance options and bulk packaging discounts.
• Enhanced sample security and reduced compound adsorption for reliable quantitative results.
• Seamless integration with chromatography and mass spectrometry platforms.

Future trends and opportunities

• Integration of smart tracking and barcode systems for sample chain-of-custody.
• Development of ultra-low adsorption materials for emerging bioanalytical workflows.
• Customization of consumables to support automation and miniaturization in high-throughput labs.
• Expansion into sustainable, low-environmental impact materials and packaging.

Conclusion

Thermo Scientific SureSTART consumables provide a versatile, performance-driven solution for chromatographic and mass spectrometric analyses.
The tiered approach ensures laboratories can balance cost, robustness and sensitivity according to their analytical needs.