SureSTART collection - Compatibility

Importance of the topic

High‐quality sample containers and consumables are essential for reliable chromatographic analysis. Proper vial and well‐plate selection minimizes contamination, carryover and adsorption, ensuring accurate quantification and reproducible results across GC, HPLC/UHPLC and MS workflows.

Goals and overview of the document

This document introduces the Thermo Scientific SureSTART collection of vials, caps, inserts, well plates and mats. It outlines compatibility with common autosamplers and presents three performance levels—everyday analysis, high‐throughput analysis and high‐performance analysis—plus a range of well plates designed for plate‐based workflows.

Methodology and used instrumentation

The SureSTART products undergo rigorous testing to meet industry standards for extractables, leachables and metal content. Key technologies include:

• AVCS (Advanced Vial Closure System) for secure sealing
• SureStop technology for consistent septum performance
• Clean‐room packing to reduce environmental contamination

Instrument compatibility covers a wide range of GC and HPLC/UHPLC autosamplers as well as detection systems such as UV/Vis, PDA, RI, ELSD, FLD, single and triple quadrupole MS, and high‐resolution Orbitrap MS.

Main findings and discussion

SureSTART supplies three distinct performance levels:

• Performance Level 1 (everyday analysis): Cost-optimized vials and caps for routine GC and HPLC/UHPLC with common detectors.
• Performance Level 2 (high‐throughput): Low metal content and extractables for regulated, high‐volume workflows, compatible with multi‐channel pipetting and UHPLC robotics.
• Performance Level 3 (high performance): Clean‐room packed, low adsorption consumables for trace‐level and high‐resolution MS analysis.

Well plates (WebSeal series) are available in 96- and 384-well formats, with polypropylene or glass-coated options. They feature inert surfaces, soft-pierce seals and ANSI SLAS compliance for automated sampling.

Benefits and practical applications

• Improved reproducibility through consistent sealing and inert materials.
• Reduced sample contamination and carryover in GC, HPLC/UHPLC and MS workflows.
• Enhanced throughput using multi‐well plates and automated autosampler compatibility.
• Scalable solutions from routine screening to trace‐level quantification.

Future trends and opportunities

As analytical demand grows, future developments may include:

• Further miniaturization of consumables for microflow chromatography.
• Integration with automated sample preparation and robotics.
• Advanced surface coatings to reduce adsorption of polar and nonpolar analytes.
• Expanded glass‐coated and inert plate formats for next-generation mass spectrometry.

Conclusion

The SureSTART collection offers a comprehensive range of consumables tailored to different analytical needs. With proven compatibility, reliable sealing technologies and clean‐room standards, these products support accurate and efficient chromatographic and mass spectrometric workflows.

References

No references cited.