KF Sample transfer set 0.5 ... 2 mL

Significance of the Topic

The Karl Fischer (KF) sample transfer set 6.5619.000 is a key accessory for automating volumetric water determinations. By integrating precise liquid handling with a titration platform, it enhances throughput, reproducibility and laboratory safety in moisture analysis.

Objectives and Overview of the Application Note

This document outlines the components and functionality of the KF sample transfer set designed for the Metrohm Sample Processor XL 789/815 and 786 Swing Head. It aims to clarify how each accessory contributes to reliable sample delivery and titrant addition in automated KF titration workflows.

Used Instrumentation

• Metrohm Sample Processor XL 789/815
• 786 Swing Head
• Dosino Dosing Unit (2 mL)
• 6.5619.000 KF Sample Transfer Set (0.5–2 mL)

Methodology and Components

The transfer set comprises multiple precision parts that ensure accurate aspiration, dispensing and sealing:

• PTFE Stopper SGJ 29 with integrated aspiration and anti-diffusion tip (6.1446.180)
• Stopper with septum SGJ (6.1448.000) plus replacement septa (6.1448.020)
• Transfer robotic arm for swing-right mounting with Luer-Lock connector (6.1462.090)
• 250 mL titration vessel SGJ (6.1464.320)
• 2 mL pipetting tubing for direct connection to the Dosino (6.1562.110)
• GL 45 glass flask, 250 mL (6.1608.090)
• Support rod mount and clamping ring (6.2001.100; 6.2013.010)
• Support mounting for Dosinos (6.2047.010)
• GL 18 screw caps for septa (6.2701.040)
• Splash protection shield (6.2751.120)
• Injection needle with vent and Luer-Lock connector (6.2816.100)
• O-rings in various sizes and materials for leak-free connections (E.301.0004; E.301.0032; E.301.0083)

Main Discussion and Benefits

Each component is selected to optimize sample integrity and minimize moisture ingress or sample carry-over. The PTFE stopper and septum allow airtight sealing while permitting automated syringe penetration. The dedicated pipetting tubing and robotic arm guarantee repeatable sample volumes, reducing operator variability. Robust glassware and support hardware maintain system stability, and safety shields protect users from reagent splashes.

Practical Applications

The complete transfer set is suited for:

• Quality control laboratories performing routine moisture analysis
• Research environments requiring high-throughput KF titrations
• Pharmaceutical, chemical and food industries where water content critically affects product performance

Future Trends and Potential Applications

Advances may include further miniaturization of fluidic components, integration of optical or conductivity sensors within the transfer path to monitor sample quality in real time, and tighter software coupling with laboratory information management systems (LIMS) for fully traceable workflows. Enhanced materials with lower moisture permeability could further improve accuracy in low-level water determinations.

Conclusion

The KF sample transfer set 6.5619.000 represents a comprehensive solution for automating volumetric Karl Fischer titrations. Its carefully engineered components work together to deliver precise sample dosing, reliable sealing and enhanced safety, supporting laboratories in achieving consistent and high-quality moisture analysis results.

Reference

No literature references were provided in the source material.