Quantitation of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS
Applications | 2011 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsoxidation, peptide, oxidized, bhp, mab, met, methionine, sites, trypsin, bioconfirm, antibody, were, monoclonal, masshunter, agilent, mfe, susceptibility, dltmisr, unmodified, treated, software, oxidization, massprofiler, analysis, recombinant, comparative, samples, axis, from, obtained, using, theoretical, containing, grouping, control, non, used, height, accurate, surfaceexposed, biopharmaceutical, ntlylqmsslr, professional, assignment, protein, digested, differential, butylhydroperoxide, mass, potential
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Identification of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS
2011|Agilent Technologies|Applications
Identification of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS Application Note Authors Abstract Ravindra Gudihal Agilent Technologies India Pvt. Ltd. Bangalore, India The identification of oxidation sites…
Key words
mab, maboxidized, oxidizedoxidation, oxidationntlylq, ntlylqsslr, sslrpeptide, peptidetrypsin, trypsinmonoclonal, monoclonalmass, masstheoretical, theoreticalmsslr, msslrbioconfirm, bioconfirmantibody, antibodyntlylqmsslr, ntlylqmsslrsequence
Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System
2017|Agilent Technologies|Applications
Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…
Key words
peptide, peptideinnovator, innovatorbiosimilar, biosimilardeamidation, deamidationcounts, countsoxidation, oxidationdltmisr, dltmisrmapping, mappingtrypsin, trypsinunmodified, unmodifiedoxi, oxiions, ionsheight, heightcharge, chargedem
Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies
2018|Agilent Technologies|Applications
Application Note Biotherapeutics Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies Using Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunter BioConfirm Software Author Linfeng Wu Agilent Technologies, Inc. Santa Clara, CA, USA Introduction Modifications such as asparagine (Asn) deamidation, aspartate…
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deamidation, deamidationpeptide, peptideasn, asndeamidated, deamidatedoxidation, oxidationunmodified, unmodifiedasp, asppeptides, peptidesquantitation, quantitationisomerization, isomerizationforms, formspenny, pennybioconfirm, bioconfirmptm, ptmmasshunter
AdvanceBio HIC: a Hydrophobic HPLC Column for Monoclonal Antibody (mAb) Variant Analysis
2019|Agilent Technologies|Applications
Application Note Biologics Research AdvanceBio HIC: a Hydrophobic HPLC Column for Monoclonal Antibody (mAb) Variant Analysis Using the Agilent 1260 Infinity II Bio-Inert LC Authors Andrew Coffey and Sandeep Kondaveeti Agilent Technologies, Inc. Abstract This Application Note describes the separation…
Key words
oxidation, oxidationmab, mabbhp, bhpoxidized, oxidizedmethionine, methioninemet, methic, hicresidues, residuesmabs, mabsmau, mauadvancebio, advancebiooxidant, oxidantshallower, shallowermonoclonal, monoclonalantibody