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Size-Exclusion Chromatography Method for Poly(A) Tail Analysis of mRNA

 

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Application Note Ion-Pair Reversed-Phase Liquid Chromatography Method for Analysis of mRNA Poly(A) Tail Heterogeneity Martin Gilar, Maissa M. Gaye Waters Corporation Abstract Messenger RNA (mRNA) biopolymers are new therapeutic modalities. Development of effective mRNA vaccines against SARS-CoV-2 virus accelerated the…
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Characterizing LNP mRNA
2024|Waters|Guides
CONSUMABLES GUIDE BOOK Characterizing LNP mRNA LC tools for purity, identity, integrity and concentration determining measurements A Changing Industry mRNA based medicine helped address the COVID-19 pandemic. The viability of using an mRNA construct as a human drug substance has…
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Application Note Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS System Jennifer M. Nguyen, Siu-Hong Chan, Bijoyita Roy, Martin Gilar, Brett Robb, Weibin Chen, Matthew A. Lauber Waters Corporation, New England Biolabs Inc. Abstract…
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Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…
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