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Application Note Biopharma/Pharma Sensitive Detection of Low-Level Byproducts in a Small Molecule Reaction by the Agilent 1260 Infinity II Prime Online LC/MS System Author Edgar Naegele Agilent Technologies, Inc. Abstract This application note demonstrates the online monitoring of a chemical…
Key words
anisylidene, anisylideneanisaldeyde, anisaldeydealdol, aldolanisaldehyde, anisaldehydeacetone, acetoneeduct, eductreaction, reactionbyproduct, byproductonline, onlinearea, areadimer, dimerreactor, reactorsim, simmin, minejection
Application Note Biopharma and Pharma Automated Reaction Monitoring by the Agilent 1260 Infinity II Prime Online LC Sampling from the reactor, dilution, quenching, and analysis Authors Christian Lautz F. Hoffmann-La Roche Ltd. Basel, Switzerland Edgar Naegele, Daniel Kutscher, and Sam…
Key words
online, onlineeduct, eductreaction, reactionanisylidene, anisylideneanisaldehyde, anisaldehydeacetone, acetonemanager, managermonitoring, monitoringinfinity, infinitydilution, dilutiondeclining, decliningsampling, samplingmolecule, moleculequantification, quantificationsample
Application Note Small Molecule Pharma Monitoring of Trace Impurities Using the Agilent 1260 Infinity II Prime Online LC System with High Dynamic Range-DAD ×103 4.0 3.6 3.2 2.8 2.4 2.0 1.6 1.2 0.8 0.4 0 0.360 0.260 0.837 0.873 0.1…
Key words
anisylidene, anisylidenebyproduct, byproductanisaldehyde, anisaldehydeeduct, eductdad, dadhdr, hdronline, onlinedynamic, dynamicreaction, reactionacetone, acetonemolecule, moleculeconcentrated, concentrateddiode, diodehigh, highsmall
Application Note Biopharma/Pharma Online Reaction Monitoring by the Agilent InfinityLab Online LC Solutions Aspirin hydrolysis with pH value-dependent reaction speed Author Edgar Naegele Daniel Kutscher Agilent Technologies, Inc. Abstract The objective of this application note is to demonstrate the online…
Key words
acetylsalicylic, acetylsalicyliconline, onlinereaction, reactionreactor, reactoracid, acidmonitoring, monitoringinfinitylab, infinitylabsalicylic, salicylicsampling, samplinghydrolysis, hydrolysisstream, streamreject, rejectaspirin, aspirinsample, sampledilution
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