CRM Ca, K, Mg, Na, P, S - Aqueous calibration solution ASTASOL® AN9097MN

Significance of the Topic

A reliable multi element aqueous calibration solution is crucial for accurate quantitative analysis in various spectrometric and electrochemical techniques. In quality assurance and research laboratories certified reference materials ensure traceability to SI units and support robust method validation and interlaboratory comparability.

Objectives and Overview of the Study

This certificate describes the production characterization and certification of the aqueous calibration solution ASTASOL AN9097MN containing Ca K Mg Na P and S at 100 mg l each at 20°C with expanded uncertainties. The reference material provides a stable and traceable standard for calibration and validation of analytical methods.

Methodology and Instrumentation

The solution is gravimetrically prepared using high purity primary compounds and diluted in a 1 percent HNO3 matrix. Traceability and verification were achieved through primary techniques and instrumental methods.

List of analytical methods used:

• Gravimetric preparation for initial concentration assignment
• Complexometric titration with EDTA for Ca and Mg using SRM NIST 928 3109a and 3131a
• ICP OES for K and Na using in house standards and SRM NIST 3152a
• Gravimetric determination for P and S using in house standard and SRM NIST 3154
• AAS AES ICP OES and ICP MS for assessment of trace impurities

Main Results and Discussion

Certified concentrations of each analyte are 100 mg l with expanded uncertainty 0.2 mg l and corresponding mass fraction values of 99.5 mg kg with 0.3 mg kg uncertainty. The density at 20°C is 1.0053 plusminus 0.0005 g cm3. Homogeneity and stability studies confirm performance over a three year shelf life when stored between 5 and 30°C. Trace impurity levels were determined for over fifty elements most below detection limits ensuring minimal interference for calibration purposes. Stability data supports a 12 month open bottle expiration following initial opening.

Benefits and Practical Application of the Method

ASTASOL AN9097MN serves as a versatile multi element standard for calibration of atomic absorption AES ICP OES ICP MS molecular absorption and electroanalytical methods. Its high purity and traceability enhance result accuracy and laboratory quality management. The standardized uncertainty values facilitate compliance with regulatory and accreditation requirements.

Future Trends and Opportunities

Next generation calibration solutions may expand analyte coverage to include trace metals and metalloids and integrate with digital calibration platforms and automation to streamline workflows. Green chemistry approaches aim to reduce acid consumption and waste. Coupling CRMs with advanced spectroscopic and hyphenated techniques will support emerging analytical challenges.

Conclusion

The ASTASOL AN9097MN certified reference material offers a robust and traceable multi element calibration solution for a wide range of analytical techniques. Rigorous gravimetric preparation primary method verification and stability testing ensure reliable performance. This CRM supports accurate quantitative analysis and meets international accreditation standards.

References

1. ISO Guide 31 Reference materials Contents of certificates and labels
2. ISO 17034 General requirements for the competence of reference material producers
3. SRM NIST 928 Fruits and Fruit Products
4. SRM NIST 3109a High Purity Calcium Carbonate
5. SRM NIST 3131a High Purity Magnesium Oxide
6. SRM NIST 3152a High Purity Sodium Nitrate
7. SRM NIST 3154 High Purity Ammonium Sulfate