CRM As, Be, Ca, Cd, Co, Cr, Cu, Fe, Li, Mg, Mn, Mo, Ni, P, Pb, Sb, Se, Sn, Sr, Ti, Tl, V, Zn - Aqueous calibration solution ASTASOL® AN9094MFN

Significance of the topic

Accurate multi‐element calibration solutions are essential for reliable quantification in various analytical techniques. Certified reference materials (CRMs) such as aqueous calibration solutions ensure traceability to SI units, enable method validation, and support quality control in environmental, industrial, and research laboratories.

Objectives and overview of the certificate

This certificate describes the preparation and certification of ASTASOL AN9094MFN, a multi‐element aqueous calibration solution. It provides certified concentrations for 22 elements at 100.0 mg/L each, along with associated uncertainties and traceability information. Key parameters such as matrix composition, density, production details, shelf life, and intended use are documented.

Methodology

The solution was prepared by gravimetric weighing of high‐purity primary compounds, ensuring direct traceability to the kilogram. Certified values were verified using primary analytical methods (gravimetry, titrimetry) and instrumental techniques (AAS, AES, ICP-OES), each calibrated against independent CRMs and SRMs. Homogeneity and stability studies demonstrated consistent performance over the declared shelf life when stored under specified conditions.

Instrumentation Used

• Atomic Absorption Spectrometry (AAS)
• Atomic Emission Spectrometry (AES)
• Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES)
• Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
• Complexometric titration with EDTA
• Gravimetric determination
• Titrimetric methods (bromatometry, iodometry)

Main results and discussion

The certified concentration for each analyte is 100.0 ± 0.2 mg/L (expanded uncertainty k=2). Density at 20 °C is 1.0349 ± 0.0005 g/cm3, yielding a mass fraction of 96.6 ± 0.3 mg/kg. Trace impurities were quantified at sub‐mg/L levels for elements such as Na, Al, Si, and rare earths, providing information for background corrections but not for calibration use.

Benefits and practical applications

• Enables accurate calibration in atomic spectrometry (AAS, AES, ICP-OES, ICP-MS).
• Supports method validation in molecular absorption and selected electroanalytical techniques.
• Ensures consistent quality control in environmental monitoring, food analysis, pharmaceuticals, and industrial QA/QC.

Future trends and applications

Advances may include development of customized multi‐element CRMs tailored to specific matrices, automation of preparation for high‐throughput needs, integration with digital certification platforms, and coupling with AI-driven data quality assessment. Expansion of traceability networks and miniaturized calibration solutions for field deployable instruments are anticipated.

Conclusion

ASTASOL AN9094MFN provides a robust, SI-traceable, multi‐element calibration solution with well-characterized performance. Its comprehensive documentation, verified uncertainties, and clear handling instructions make it a valuable tool for analytical laboratories seeking to maintain high standards of precision and accuracy.

References

• NIST Standard Reference Materials (SRM series for method verification)
• TraceCERT 92615 for tin calibration
• In-house solid and liquid CRMs used as secondary standards