CRM Ag, Al, As, Ba, Be, Bi, Ca, Cd, Co, Cr, Cs, Cu, Fe, Ga, In, K, Li, Mg, Mn, Na, Ni, Pb, Rb, Se, Sr, Tl, U, V, Zn - Aqueous calibration solution ASTASOL® AN9117MN

Significance of the Topic

This certificate describes a multi‐element aqueous certified reference material (CRM) ASTASOL® AN9117MN used for calibration and validation in a wide range of analytical techniques. Accurate CRMs are essential for traceable, reproducible measurements in atomic spectrometry, molecular absorption and electroanalytical methods, supporting quality assurance in environmental, clinical, industrial and research laboratories.

Objectives and Overview of the Certificate

The primary aim is to document the preparation, certification, homogeneity and stability of ASTASOL® AN9117MN, ensuring compliance with ISO Guide 31 and ISO 17034. The certificate outlines:

• List of 28 essential elements at a nominal concentration of 10.00 mg/L.
• Matrix composition and physical properties (density, temperature).
• Traceability, uncertainty evaluation and intended use.

Methodology and Instrumentation

The CRM was prepared gravimetrically from high‐purity primary compounds in 5 % HNO3 (v/v) using sub‐boiled acid and ultrapure water. Certification relies on:

• Gravimetric and titrimetric primary methods for direct SI traceability.
• Verification by instrumental techniques: atomic absorption spectrometry (AAS), atomic emission spectrometry (AES), ICP‐OES and ICP‐MS calibrated with independent reference solutions (e.g. NIST SRMs, TraceCERT).

Main Results and Discussion

Certified values at 20 °C for each analyte:

• 10.00 ± 0.05 mg/L (expanded uncertainty, k = 2).
• 9.75 ± 0.07 mg/kg (derived from density).

Matrix density: 1.0257 ± 0.0005 g/cm3 at 20 °C. Homogeneity tests and stability studies confirm consistent concentration and shelf life of 12 months from production and 12 months after opening.

Benefits and Practical Applications

ASTASOL® AN9117MN provides:

• Reliable calibration for multi‐element measurements in environmental, food, pharmaceutical and industrial samples.
• Traceable uncertainty budgets enhancing method validation and inter‐laboratory comparability.
• Ready‐to‐use solution reducing preparation time and contamination risk.

Future Trends and Opportunities

Emerging developments in CRM technology include:

• Expansion of element panels to cover ultra‐trace and isotope ratio applications.
• Adoption of digital metadata and blockchain for enhanced traceability.
• Miniaturized high‐throughput calibration formats for automated and micro‐sampling instruments.

Conclusion

The ASTASOL® AN9117MN CRM meets stringent ISO requirements, offering a robust tool for accurate, traceable multi‐element analysis. Its validated homogeneity, stability and broad instrument compatibility make it a valuable resource for laboratories seeking high‐quality calibration standards.

Reference

• ISO Guide 31: Reference materials—Contents of certificates and labels.
• ČSN EN ISO 17034:2017—General requirements for reference material producers.
• ISO 9001, ISO/IEC 17025:2018—Quality management and testing laboratory accreditation.