CRM As, Be, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Mo, Ni, Pb, Sb, Se, Ti, Tl, V, Zn - Aqueous calibration solution ASTASOL® AN9098MN

Significance of the Topic

A reliable multi-element aqueous calibration solution underpins accurate quantification in atomic and molecular spectrometry as well as electroanalytical techniques. Certified reference materials (CRMs) like ASTASOL® AN9098MN ensure traceability, comparability and validation of analytical methods across laboratories and industries, supporting quality control and regulatory compliance.

Objectives and Overview

This document presents the certification of ASTASOL® AN9098MN, a 19-element multi-analyte solution in 5% HNO₃. The study aims to establish certified concentrations, uncertainties and traceability, validate homogeneity and stability, and define handling and storage conditions.

Methodology and Instrumentation

The CRM was prepared gravimetrically, ensuring direct SI traceability. Purity of starting compounds ranged from 99.95% to 99.9995%. The matrix is 5% sub-boiled HNO₃ in ultrapure water (≥18 MΩ·cm). Density at 20 °C was determined (1.0410 ± 0.0005 g·cm⁻³).

• Primary characterization: Gravimetric and titrimetric determinations for As, Be, Mo, Ti and others.
• Instrumental verification: AAS, AES, ICP-OES, ICP-MS calibrated with SRM NIST reference solutions and in-house CRMs.

Main Results and Discussion

Certified concentrations at 20 °C are 100.0 ± 0.2 mg·L⁻¹ (96.1 ± 0.3 mg·kg⁻¹). Homogeneity tests confirm uniform distribution of all analytes within the batch. Stability studies under recommended storage (5–30 °C, sealed) support a 5-year shelf life and 12-month expiry after opening. Trace impurities were quantified at sub-µg·L⁻¹ levels to inform users but are not intended for calibration.

Benefits and Practical Applications

ASTASOL® AN9098MN enables simultaneous calibration of up to 19 elements, reducing preparation time and potential errors. It is suitable for method validation, instrument performance checks and inter-laboratory comparisons in environmental, food, pharmaceutical and industrial laboratories.

Future Trends and Applications

Expanding multi-element solutions to include emerging contaminants and ultra-trace levels will meet evolving analytical demands. Integration with hyphenated techniques and automation of CRM handling can further enhance laboratory efficiency and data quality.

Conclusion

ASTASOL® AN9098MN provides a robust, SI-traceable calibration reference for a wide range of spectrometric and electroanalytical methods. Its certified concentrations, validated homogeneity and stability, and detailed handling instructions ensure reliable analytical performance and support high-quality data generation.

Reference

Primary methods and traceability were established using SRM NIST reference materials (e.g. 3103a, 3105a, 3108, 3112a) and in-house standards.