Agilent Drivers for Thermo Scientific Chromeleon 7 Release Notes – Revision 3.1

Importance of the Topic

The Agilent Drivers for Thermo Scientific Chromeleon 7 are critical for laboratories that rely on integrated chromatographic workflows under regulated environments. By enabling unified control of Agilent GC, LC, and headspace instruments within the Thermo Scientific Chromeleon CDS, the drivers reduce instrument interfacing complexity and support compliance and validation requirements.

Objectives and Overview of the Release Notes

This release note documents the enhancements and fixes introduced in Revision 3.1 of the Agilent Drivers for Thermo Scientific Chromeleon 7. It provides a structured guide to new instrument support, compatibility prerequisites, installation and upgrade procedures, and known issues along with their resolutions.

Methodology and Instrumentation

The drivers implement an Instrument Control Framework based on Microsoft .NET, integrating updated GC, LC/CE, ELSD, and headspace drivers. Revision 3.1 adds native support for:

• Agilent 8850 single-channel GC
• Agilent 8697 XL 120-vial headspace sampler
• Agilent G7167C 1260 Infinity II Hybrid Multisampler
• Universal SerialNo property reporting for all modules

Compatibility

Supported platforms include Chromeleon 7.2.10 MUf and above through 7.3.2 MUa, Microsoft Windows 10/11 and Windows Server 2016–2022. Language support in the LC driver covers English, Chinese, Japanese, and Portuguese; the GC driver adds Russian. Third-party modules tested for mixed-instrument configurations include the Thermo Fisher Corona Veo CAD and WPS-3000 autosampler, with documented limitations.

Main Results and Discussion

Revision 3.1 consolidates driver stability with updated firmware and addresses known issues across GC, headspace, and ELSD control. Enhanced utilities include a GC Method Resolution Wizard and expanded software verification through the Agilent Software Verification Tool (SVT), supporting silent verification and Chromeleon IQ integration.

Benefits and Practical Applications

Users gain immediate access to new Agilent hardware within existing Chromeleon sequences, simplified configuration updates, and comprehensive audit trails for regulatory compliance. The SerialNo property enhances traceability, while dynamic licensing and method migration tools reduce administrative overhead.

Future Trends and Opportunities

Looking ahead, Agilent plans to extend support for its emerging Infinity III series and further optimize .NET CLR 4 compatibility. Potential additions include advanced 2D-LC workflows, tighter MS coupling, and automated buffer and method scouting solutions.

Conclusion

Agilent Drivers for Thermo Scientific Chromeleon 7 Revision 3.1 delivers robust instrument support, streamlined installation, and comprehensive validation tools. It strengthens the integration of Agilent chromatography hardware under the Chromeleon CDS, helping users maintain high productivity and regulatory compliance.

References

• No external literature referenced in the source document