Agilent LC & CE Drivers 3.9 - Release Note

Significance of the Topic

LC and capillary electrophoresis (CE) drivers are critical software components facilitating instrument control and integration in chromatographic systems. Release 3.9 enhances hardware support for level sensing, injector programming, and prediction capabilities, addressing user demands for reliability, automation, and efficiency in analytical labs.

Objectives and Overview of the Study

This document provides an overview of the major features, compatibility, installation guidelines, and updates introduced in Agilent LC & CE Drivers version 3.9. It targets end users and system administrators requiring clarity on new functionalities, system prerequisites, and best practices for deployment.

Methodology and Instrumentation

Underlying the 3.9 release are new firmware and software modules designed to communicate with varied LC and CE hardware. Key modules affected include the G7175A InfinityLab Level Sensing unit and autosampler controllers. The development process included extensive compatibility testing across operating systems (Windows Server 2016–2022, Windows 10–11) and with multiple Chromatographic Data Systems (OpenLab CDS, ChemStation Edition, EZChrom, MassHunter).

Instrumentation Used

The release notes reference hardware and firmware versions for:

• G7175A InfinityLab Level Sensing
• G716x and G713x autosampler modules (Multisamplers, Vialsamplers)
• Pump models (G131x, G420x, G711x, G7120A, etc.)
• Detectors (VWD, DAD, ELSD, FLD, RID)
• Valve drives (G1170A Universal, various port configurations)
• Fraction collectors (G1364 series, G5664 series, G7159B)

Main Results and Discussion

Version 3.9 introduces:

• Support for InfinityLab Level Sensing hardware and prediction algorithms to monitor solvent levels in real time.
• Expanded Easy Injector Program features to streamline sampler method creation.
• Enhanced compatibility matrix detailing supported OS, CDS platforms, localization options, and backward compatibility guidelines.
• Simplified installation and update processes via MSI packages for OpenLab and MassHunter environments.

These enhancements improve user workflows, reduce setup errors, and extend automation capabilities.

Benefits and Practical Applications of the Method

The new level sensing integration prevents run interruptions due to low solvent, while predictive alerts enable proactive maintenance. The enriched injector programming interface reduces method setup time and potential errors. Broad OS and CDS compatibility ensure seamless integration in diverse lab environments.

Future Trends and Potential Applications

Ongoing development will likely focus on deeper integration of predictive analytics, AI-driven method optimization, and expanded support for multi-dimensional LC (2D-LC) and preparative workflows. Enhanced user interfaces and cloud-based monitoring tools will further streamline routine analyses and remote system management.

Conclusion

Agilent LC & CE Drivers 3.9 offer significant improvements in hardware support, user experience, and system compatibility. By incorporating level sensing and advanced injector programming, this release strengthens the reliability and efficiency of chromatographic workflows across research, quality control, and preparative applications.