Comprehensive analysis of low abundant mannose glycopeptides in peptide mapping of adalimumab
Applications | 2020 | SCIEXInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, Capillary electrophoresis
IndustriesProteomics , Clinical Research
ManufacturerSCIEX
Key wordscesi, glycopeptides, forward, adalimumab, mapping, peptide, electrophoretically, glycan, rolling, abundant, antibodies, modifications, glycopeptide, ptms, mannose, proteins, recombinant, translational, post, identification, fucosylate, collision, slope, various, nanoliters, therapeutic, characterize, monoclonal, proteinpilottm, low, peakview, high, humira, technology, peptides, well, confirmation, species, sequence, production, immunogenic, produced, characterization, cze, deamidated, separate, ability, energy, nanospray, lowered
Similar PDF
Optimized digestion procedure and characterization for monoclonal antibodies and proteins by CESI-MS
2020|SCIEX|Applications
Optimized digestion procedure and characterization for monoclonal antibodies and proteins by CESI-MS Featuring CESI 8000 Plus and TripleTOF® 6600+ LC-MS/MS System Zuzana Demianova1, Anna Lou1 and Sahana Mollah2 1 SCIEX, Brea, CA; 2 SCIEX, Redwood City, CA Peptide mapping by…
Key words
ddi, ddiforward, forwardcesi, cesiemitter, emitterdip, dipwater, waterpeptide, peptidereverse, reversemapping, mappingisotachophoresis, isotachophoresisdigestion, digestionbge, bgepsi, psielectrophoresis, electrophoresisadalimumab
Accelerating monoclonal antibody peptide mapping with high acquisition speed Orbitrap-based MS
2020|Thermo Fisher Scientific|Applications
APPLICATION NOTE 73672 Accelerating monoclonal antibody peptide mapping with high acquisition speed Orbitrap-based MS Authors: Phil Widdowson, Amy Claydon, Tom Buchanan Thermo Fisher Scientific, Hemel Hempstead, UK Keywords: Peptide mapping, monoclonal antibody, mAb, post-translational modification, PTM, high throughput analysis, golimumab,…
Key words
golimumab, golimumabterminal, terminaldeamidation, deamidationglycosylation, glycosylationpeptide, peptidelysine, lysinemodification, modificationmapping, mappingdigest, digestrelative, relativeoxidation, oxidationpeptides, peptidessmart, smartmodifications, modificationspyroglu
Glycopeptide Characterization for Various Monoclonal Antibodies Using the Agilent 6545XT AdvanceBio LC/Q-TOF
2019|Agilent Technologies|Applications
Application Note Biotherapeutics and Biosimilars Glycopeptide Characterization for Various Monoclonal Antibodies Using the Agilent 6545XT AdvanceBio LC/Q-TOF Author David L. Wong Agilent Technologies, Inc. Introduction Monoclonal antibodies (mAbs) and their derivatives represent a very complex but important class of biopharmaceutical…
Key words
glycopeptides, glycopeptidesmapping, mappingglycan, glycanglycopeptide, glycopeptidemab, mabadvancebio, advancebiopeptide, peptideassaymap, assaymapbravo, bravotkpreeqynstyr, tkpreeqynstyrhilic, hilicpeptides, peptideswere, weremabs, mabscolumn
How to Determine Glycan Profiles of Biopharmaceuticals from Peptide Mapping Data
2021|Bruker|Applications
How to Determine Glycan Profiles of Biopharmaceuticals from Peptide Mapping Data A new and sensitive approach combining BioPharma Compass, PASEF and VIP-HESI Abstract Glycosylation is a common critical quality attribute (CQA) of therapeutic proteins and needs to be characterized during…
Key words
glycan, glycanpeptide, peptideglycopeptide, glycopeptidetryptic, trypticcompositions, compositionsmapping, mappingsearch, searchpasef, paseftimstof, timstofbruker, brukerglycans, glycansglycopeptides, glycopeptidesspectra, spectrausing, usingwere