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A Modified Orbitrap Tribrid Mass Spectrometer with Real Time Search and Advanced Spectral Processing Enhances Multiplexed Proteome Coverage and Quantification Accuracy

Posters | 2019 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Proteomics
Manufacturer
Thermo Fisher Scientific
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An Orbitrap Eclipse Tribrid Mass Spectrometer with Real-Time Search Enhances Multiplexed Proteome Coverage and Quantitation Accuracy Aaron M. Robitaille 1, Romain Huguet 1, Derek J. Bailey 1, Graeme McAlister 1, Arne Kreutzmann 2, Daniel Mourad 2, Zoon Chan 3,Daniel Lopez-Ferrer…
Key words
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APPLICATION NOTE 65729 Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer Authors: Aaron M. Robitaille1, Romain Huguet1, Ryan Bomgarden2, Jesse D. Canterbury1, Daniel Lopez-Ferrer1 Thermo Fisher Scientific, San Jose, CA…
Key words
search, searchtmt, tmtreal, realcomet, cometxcorr, xcorrsps, spstribrid, tribridorbitrap, orbitrapmass, masstime, timeeclipse, eclipsequantitation, quantitationinterference, interferenceaccuracy, accuracyengine
New Quadrupole-Ion Trap-Orbitrap Mass Spectrometer Combined with Real Time Search Enhances Proteome Coverage and Quantification Accuracy in Multiplexing Workflows Xiangyun Yang, Xiujie Sun, Yue Zhou, Thermo Fisher Scientific, Building 6, 27 Xinjinqiao Road, Shanghai, China, 210006 Results: RTS-SPS-MS3 method on…
Key words
psm, psmquantified, quantifiedproteins, proteinstmt, tmtpeptides, peptidesdia, diapsms, psmssps, spsindex, indexlabeled, labeledinterference, interferencepeptide, peptideplasma, plasmacount, countidentified
Extending Capabilities of Real-Time Database Search on the Orbitrap Eclipse Tribrid Mass Spectrometer for Multiplexed Proteomics Yang Liu1 , William D. Barshop1, Amirmansoor Hakimi1, Jesse D. Canterbury1, Romain Huguet1, Rosa Viner1 1Thermo 1 Fisher Scientific, San Jose, CA, USA The…
Key words
ecoli, ecolirts, rtssps, spssearch, searchreal, realfdr, fdrtmt, tmteclipse, eclipsepeptides, peptidesreporter, reporterquantified, quantifiedclose, closefragments, fragmentsorbitrap, orbitrapmultiplexed
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