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Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer

Applications | 2020 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Clinical Research
Manufacturer
Thermo Fisher Scientific
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An Orbitrap Eclipse Tribrid Mass Spectrometer with Real-Time Search Enhances Multiplexed Proteome Coverage and Quantitation Accuracy Aaron M. Robitaille 1, Romain Huguet 1, Derek J. Bailey 1, Graeme McAlister 1, Arne Kreutzmann 2, Daniel Mourad 2, Zoon Chan 3,Daniel Lopez-Ferrer…
Key words
sps, spssearch, searchtmt, tmtreal, realtribrid, tribridauto, autoorbitrap, orbitraprts, rtsmodified, modifiedinterference, interferencetime, timeion, ionmass, massspectrometer, spectrometerquantitation
POSTER NOTE 65536 A Modified Orbitrap Tribrid A Modified Orbitrap Tribrid Mass Spectrometer with Real Time Search and Advanced Spectral Processing EnhancesCov Multiplexed Proteome Multiplexed ProteomeAaron Coverage and1,Quantification M. Robitaille Romain Huguet 1, Accuracy Derek J. Bailey 1, G 1…
Key words
sps, spstmt, tmttribrid, tribridrts, rtssearch, searchreal, realmodified, modifiedauto, autoorbitrap, orbitrapspssps, spsspsinterference, interferencespectrometer, spectrometertime, timeion, ionmass
Implementing Comet search engine into Proteome Discoverer to improve TMT Real-Time Search data processing 1 Yang Liu, 2Frank Berg, 1 William D. Barshop, 1Jesse D. Canterbury, 1David Horn, 1David Bergen, 1Romain Huguet, 1Rosa Viner 1Thermo Fisher Scientific, San Jose, CA,…
Key words
comet, cometpercolator, percolatorsequest, sequestdecoy, decoysearch, searchdiscoverer, discovererpsm, psmproteome, proteomerts, rtsfixvalue, fixvalueprotein, proteinfix, fixtribrid, tribridsequestht, sequesthtquan
A TMTpro 18plex Proteomics Standard for Assessing Protein Measurement Accuracy and Precision Jae Choi1, Yang Liu2, Rosa Viner2, Joao A. Paulo3, Ryan Bomgarden1 1Thermo Fisher Scientific, Rockford, IL; 2Thermo Fisher Scientific, San Jose, CA; 3Harvard Medical School, Boston, MA ABSTRACT…
Key words
rts, rtsprotein, proteinidentifications, identificationsgroups, groupsagc, agctribrid, tribridparental, parentaleclipse, eclipsepsms, psmsstrains, strainsorbitrap, orbitrapscan, scanquan, quanicsw, icswcid
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