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Variable Data-Independent Acquisition (vDIA) Delivers High Selectivity and Sensitivity in Combined Targeted and Untargeted Analyses for Small Molecules

 

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Olaf Scheibner, Maciej Bromirski, Thermo Fisher Scientific, Bremen, Germany Appli cat i on N ote 6 1 4 Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Meat, Plasma, and Milk on a Q Exactive Focus LC-MS System Key…
Key words
vdia, vdiafull, fullscan, scanions, ionsfragment, fragmentexactive, exactivemuscle, musclewindows, windowsfocus, focusrange, rangeindependent, independentveterinary, veterinarymass, masstargeted, targetedmetronidazole
Olaf Scheibner, Maciej Bromirski, Thermo Fisher Scientific, Bremen, Germany Appli cat i on N ote 6 1 4 Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Meat, Plasma, and Milk on a Q Exactive Focus LC-MS System Key…
Key words
vdia, vdiafull, fullscan, scanions, ionsfragment, fragmentexactive, exactivemuscle, musclewindows, windowsfocus, focusrange, rangeindependent, independentveterinary, veterinarymass, masstargeted, targetedmetronidazole
screening remain fully available as in AIF. Methods Sample Preparation 150 veterinary drug standards (50 ppb for each single compound) were mixed and diluted with methanol-extracted blank matrix of mixed piglet feed into 50 ppt, 500 ppt, 5 ppb, and…
Key words
vdia, vdiaaif, aifparent, parentions, ionsabundance, abundancescan, scanrelative, relativescreening, screeningfull, fullorbitrap, orbitrapbrombuterol, brombuterolhydrochloride, hydrochloridehcd, hcdtriggering, triggeringddms
Paul Zomer and Hans Mol; RIKILT Wageningen UR, The Netherlands Olaf Scheibner and Maciej Bromirski; Thermo Fisher Scientific, Bremen, Germany Key Words Q Exactive Focus, pesticides analysis, mycotoxin analysis, veterinary drugs analysis, high resolution, data independent acquisition, sensitivity, selectivity Goal…
Key words
vdia, vdiadetects, detectsaif, aiffood, foodprecursor, precursordata, dataindependent, independentwheat, wheatsupplement, supplementapple, appleliver, liverscopolamin, scopolaminexactive, exactivefeed, feedcoinciding
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