Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence DetectionApplications | 2020 | WatersInstrumentation
Consumables, HPLC, LC columns, GPC/SEC
Industries
Clinical Research
Manufacturer
Waters
Key words

 

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Anion-Exchange Chromatography for Determining Emptyand Full Capsid Contents in Adeno-Associated VirusHua Yang, Stephan Koza, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■Empty and full AAV capsid separationRecombinant adeno-associated virus (AAV) vector has been increasinglyand quantification by Protein-Pakused as a vehicle...
Key words
empty, emptycapsid, capsidcapsids, capsidsaav, aavaex, aexfull, fullvirus, virusadeno, adenoserotypes, serotypesanion, anionassociated, associatedminutes, minutesdetermining, determiningexchange, exchangeres
Optimizing Adeno-Associated Virus (AAV) Capsid Protein AnalysisUsing UPLC and UPLC-MSXimo Zhang, Stephan Koza, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAn optimized LC-MS solution for theRecombinant adeno-associated viruses (rAAVs) are the most widelyseparation and intact mass analysisused...
Key words
capsid, capsidaav, aavadeno, adenouplc, uplcvirus, virusassociated, associatedproteins, proteinsoptimizing, optimizingraav, raavtherapy, therapymass, massflr, flrgene, geneacquity, acquityviral
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsiex, iexmeasure, measurefull, fullrplc, rplcmonitoring, monitoringcharacterization
Advanced TherapeuticMedicinal Products:Adeno-associated Virus (AAV) The Promise of Viral Vector GeneTherapy using AAV7000Monogenic Diseases20 of 224 YearsChildren with spinalmuscular atrophy (SMA)given the ability to thrivewith Zolgensma® (AAV) at91% efficacy1.and counting of sustainedefficacy of one dose ofLuxturna® (AAV), providingfunctional vision to thosewith...
Key words
aav, aavbioprocess, bioprocessglossary, glossarycapsid, capsidmapping, mappingdiscovery, discoverygene, generegulatory, regulatorytherapy, therapydevelopment, developmentspecifications, specificationsvirus, virusadeno, adenoviral, viraltransduction

Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence DetectionApplications | 2020 | WatersInstrumentation
Consumables, HPLC, LC columns, GPC/SEC
Industries
Clinical Research
Manufacturer
Waters
Key words

 

Similar PDF

Toggle
Anion-Exchange Chromatography for Determining Emptyand Full Capsid Contents in Adeno-Associated VirusHua Yang, Stephan Koza, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■Empty and full AAV capsid separationRecombinant adeno-associated virus (AAV) vector has been increasinglyand quantification by Protein-Pakused as a vehicle...
Key words
empty, emptycapsid, capsidcapsids, capsidsaav, aavaex, aexfull, fullvirus, virusadeno, adenoserotypes, serotypesanion, anionassociated, associatedminutes, minutesdetermining, determiningexchange, exchangeres
Optimizing Adeno-Associated Virus (AAV) Capsid Protein AnalysisUsing UPLC and UPLC-MSXimo Zhang, Stephan Koza, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAn optimized LC-MS solution for theRecombinant adeno-associated viruses (rAAVs) are the most widelyseparation and intact mass analysisused...
Key words
capsid, capsidaav, aavadeno, adenouplc, uplcvirus, virusassociated, associatedproteins, proteinsoptimizing, optimizingraav, raavtherapy, therapymass, massflr, flrgene, geneacquity, acquityviral
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsiex, iexmeasure, measurefull, fullrplc, rplcmonitoring, monitoringcharacterization
Advanced TherapeuticMedicinal Products:Adeno-associated Virus (AAV) The Promise of Viral Vector GeneTherapy using AAV7000Monogenic Diseases20 of 224 YearsChildren with spinalmuscular atrophy (SMA)given the ability to thrivewith Zolgensma® (AAV) at91% efficacy1.and counting of sustainedefficacy of one dose ofLuxturna® (AAV), providingfunctional vision to thosewith...
Key words
aav, aavbioprocess, bioprocessglossary, glossarycapsid, capsidmapping, mappingdiscovery, discoverygene, generegulatory, regulatorytherapy, therapydevelopment, developmentspecifications, specificationsvirus, virusadeno, adenoviral, viraltransduction
 

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