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High Resolution Size-Exclusion Chromatography Separations of mAb Aggregates, Monomers, and Fragments using BioResolve SEC mAb Columns on UPLC, UHPLC, and HPLC Chromatography Systems

 

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[ CARE AND USE MANUAL ] BioResolve SEC mAb Guard and Columns CONTENTS I. INTRODUCTION II. SEC ANALYSIS OF MONOCLONAL IgG ANTIBODY AGGREGATES, MONOMERS, AND FRAGMENTS a. Considerations b. Determining Extra-Column LC System Dispersion c. Selecting the Appropriate …
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[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…
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[ CARE AND USE MANUAL ] XBridge Premier Protein SEC 250 Å, 2.5 µm Columns CONTENTS I. INTRODUCTION Thank you for choosing a Waters™ SEC Column. The XBridge™ I. INTRODUCTION II. SEC ANALYSIS OF PROTEIN AGGREGATES, MONOMERS, AND FRAGMENTS…
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[ APPLICATION NOTE ] Impact of LC System Dispersion on the Size-Exclusion Chromatography Analysis of Monoclonal IgG Antibody Aggregates and Fragments: Selecting the Optimal Column for Your Method Stephan M. Koza, Corey E. Reed, and Weibin Chen Waters Corporation, Milford,…
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