High Resolution Size-Exclusion Chromatography Separations of mAb Aggregates, Monomers, and Fragments using BioResolve SEC mAb Columns on UPLC, UHPLC, and HPLC Chromatography SystemsApplications | 2020 | WatersInstrumentation Consumables, HPLC, LC columns, GPC/SECIndustriesClinical ResearchManufacturerWatersKey wordsmab, dispersion, variant, bioresolve, sec, size, bio, acquity, system, waters, uplc, resolution, separations, aggregates, column, columns, standard, tailing, performance, effect, peak, fab, systems, alliance, arc, tested, help, cropped, intending, class, hmwp, plates, exclusion, slightly, dispersions, understanding, ensure, high, warren, quantify, bill, hydrolytic, generation, main, hinge, spreading, using, between, each, dibasic
BioResolve SEC mAb Guard Columns for Production Process and Formulation Development Samples
Application NoteBioResolve SEC mAb Guard Columns forProduction Process and FormulationDevelopment SamplesStephan M. Koza, Weibin ChenWaters CorporationThis is an Application Brief and does not contain a detailed Experimental section.AbstractSize-exclusion chromatography (SEC) is commonly used to support the development ofbiotherapeutic protein products...
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Impact of LC System Dispersion on the Size-Exclusion Chromatography Analysis of Monoclonal IgG Antibody Aggregates and Fragments: Selecting the Optimal Column for Your Method
Impact of LC System Dispersion on the Size-Exclusion ChromatographyAnalysis of Monoclonal IgG Antibody Aggregates and Fragments:Selecting the Optimal Column for Your MethodStephan M. Koza, Corey E. Reed, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■An educational and systematicHistorically, native size-exclusion...
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High Resolution and High Throughput Size-Exclusion Chromatography Separations of IgG Antibody Aggregates and Fragments on UHPLC and HPLC Systems with 2.5 μm BEH Particles
High Resolution and High Throughput Size-Exclusion ChromatographySeparations of IgG Antibody Aggregates and Fragments on UHPLCand HPLC Systems with 2.5 µm BEH ParticlesStephan M. Koza and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■A performance comparison of Waters™Size-exclusion chromatography (SEC) has been...
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Comparison of Sub-3-μm HP-SEC Columns for the Analysis of IgG Antibody Aggregates (HMWS) and Fragments (LMWS)
Application NoteComparison of Sub-3-µm HP-SEC Columnsfor the Analysis of IgG Antibody Aggregates(HMWS) and Fragments (LMWS)Stephan M. Koza, Weibin ChenWaters CorporationThis is an Application Brief and does not contain a detailed Experimental section.AbstractThe performance of the Waters BioResolve SEC mAb, 200...
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