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Impact of LC System Dispersion on the Size-Exclusion ChromatographyAnalysis of Monoclonal IgG Antibody Aggregates and Fragments:Selecting the Optimal Column for Your MethodStephan M. Koza, Corey E. Reed, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■An educational and systematicHistorically, native size-exclusion...
Key words
hmws, hmwsdispersion, dispersionaggregates, aggregatesigg, iggexclusion, exclusionantibody, antibodyacquity, acquitybio, biominutes, minutesimpact, impactsize, sizemonomer, monomersystem, systemmonoclonal, monoclonaluplc
Application NoteSize Exclusion Chromatography MethodTransfer of a Monoclonal Antibody AcrossUHPLC SystemsZhimin Li, Paula Hong, Patricia R. McConvilleWaters CorporationThis is an Application Brief and does not contain a detailed Experimental section. AbstractThis application brief demonstrates a size-exclusion chromatography method transfer formonoclonal antibody...
Key words
hmw, hmwexclusion, exclusionbio, bioarc, arcacquity, acquitysec, secchromatography, chromatographysize, sizesystem, systemmethod, methodtransfer, transferhmws, hmwsreproduced, reproduceddegradants, degradantstunable
Impact of Instrument and Detector Characteristics on Size ExclusionChromatography Method Transfer Across Biocompatible UHPLC SystemsZhimin Li, Paula Hong, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■INTRODUCTIONBiocompatible system for SEC analysisIn the biopharmaceutical industry, it is common to evaluate biotherapeutics,for...
Key words
arc, archmw, hmwbio, biolmw, lmwacquity, acquitypda, pdaexclusion, exclusionmonomer, monomermean, meanrsd, rsdtransfer, transfersize, sizebiocompatible, biocompatiblemethod, methodsec
Evaluating the Performance of the ACQUITY Arc Bio UHPLC System forthe Size-Exclusion Chromatography Analysis of a Monoclonal AntibodyCorey E. Reed, Stephan M. Koza, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■ACQUITY™ Arc™ Bio UHPLC provides theSize-exclusion chromatography (SEC) is the...
Key words
acquity, acquitybio, bioarc, arclmw, lmwminutes, minutesuplc, uplcalliance, alliancesystem, systemxbridge, xbridgehmw, hmwfragment, fragmentclass, classtrastuzumab, trastuzumabmonoclonal, monoclonalmonomer
 

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Impact of LC System Dispersion on the Size-Exclusion ChromatographyAnalysis of Monoclonal IgG Antibody Aggregates and Fragments:Selecting the Optimal Column for Your MethodStephan M. Koza, Corey E. Reed, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■An educational and systematicHistorically, native size-exclusion...
Key words
hmws, hmwsdispersion, dispersionaggregates, aggregatesigg, iggexclusion, exclusionantibody, antibodyacquity, acquitybio, biominutes, minutesimpact, impactsize, sizemonomer, monomersystem, systemmonoclonal, monoclonaluplc
Application NoteSize Exclusion Chromatography MethodTransfer of a Monoclonal Antibody AcrossUHPLC SystemsZhimin Li, Paula Hong, Patricia R. McConvilleWaters CorporationThis is an Application Brief and does not contain a detailed Experimental section. AbstractThis application brief demonstrates a size-exclusion chromatography method transfer formonoclonal antibody...
Key words
hmw, hmwexclusion, exclusionbio, bioarc, arcacquity, acquitysec, secchromatography, chromatographysize, sizesystem, systemmethod, methodtransfer, transferhmws, hmwsreproduced, reproduceddegradants, degradantstunable
Impact of Instrument and Detector Characteristics on Size ExclusionChromatography Method Transfer Across Biocompatible UHPLC SystemsZhimin Li, Paula Hong, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■INTRODUCTIONBiocompatible system for SEC analysisIn the biopharmaceutical industry, it is common to evaluate biotherapeutics,for...
Key words
arc, archmw, hmwbio, biolmw, lmwacquity, acquitypda, pdaexclusion, exclusionmonomer, monomermean, meanrsd, rsdtransfer, transfersize, sizebiocompatible, biocompatiblemethod, methodsec
Evaluating the Performance of the ACQUITY Arc Bio UHPLC System forthe Size-Exclusion Chromatography Analysis of a Monoclonal AntibodyCorey E. Reed, Stephan M. Koza, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■ACQUITY™ Arc™ Bio UHPLC provides theSize-exclusion chromatography (SEC) is the...
Key words
acquity, acquitybio, bioarc, arclmw, lmwminutes, minutesuplc, uplcalliance, alliancesystem, systemxbridge, xbridgehmw, hmwfragment, fragmentclass, classtrastuzumab, trastuzumabmonoclonal, monoclonalmonomer
 

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