A high-resolution accurate mass multi-attribute method for critical quality attribute monitoring and new peak detection
Applications | 2019 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordsnistmab, intensity, mam, peptide, chromeleon, stressed, prtc, ratio, thermo, finder, scientific, retention, counts, biopharma, integration, software, stress, mass, min, vanquish, settings, peak, npd, cqa, workbook, time, value, deamidated, maximum, modifications, threshold, relative, deamidation, processing, frames, were, thermal, oxidation, abundant, agc, horizon, attribute, workflow, isotopes, cqas, new, resolution, component, width, charge
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Headline can be placed within an image area for flexibility HR Multi-Attribute Method for biopharma analysis DEAMIDATION CQA Resolution matters from research to routine D A C P K D C D Q K S-S A Y C S K…
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TECHNICAL NOTE 73535 Performing the biopharmaceutical multi-attribute method (MAM) Keywords: Multi-attribute method, MAM, HR MAM, BioPharma Finder, Chromeleon Chromatography Data System, CDS, product quality attributes, PQAs, critical quality attributes, CQAs, high resolution, accurate mass, HRAM, compliance Introduction The Multi-Attribute Method…
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Refinement of HR Multi-Attribute Method from Sample Preparation to Data Analysis Haichuan Liu, Hao Yang, and Min Du, Thermo Fisher Scientific, San Jose, USA, 95134 Figure 7. Effect of S-Lens RF on glycopeptide EEQYN[A1G0F]STYR ABSTRACT RESULTS The Thermo Scientific™ HR…
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The MAM 2.0 workflow enables seamless transition from research and development to quality control
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Key words
mam, mamexploris, explorisnistmab, nistmaborbitrap, orbitrappqas, pqaspqa, pqapeptide, peptideeworkflow, eworkflowmapping, mappingmass, massquality, qualitychromeleon, chromeleonmodification, modificationvanquish, vanquishmethod