Agilent LC & CE Drivers 3.1 - Release Note

Importance of the topic

The Agilent LC & CE Drivers 3.1 release is critical for laboratories seeking to integrate new hardware modules, enhance existing workflows, and maintain software compatibility across modern chromatography systems. Its support for novel preparative autosamplers and fraction collectors, improved pressure management, and expanded language options underscores its role in boosting system performance and user accessibility.

Objectives and overview

This document summarizes the key enhancements delivered in version 3.1 of the LC & CE Drivers. It outlines the introduction of new modules, improvements to existing features, system compatibility requirements, and guidance on recommended firmware and installation procedures.

Methodology and instrumentation

• Introduction of G7158B 1290 Infinity II Preparative Open-bed Autosampler / Fraction Collector, represented by a preparative injector driver (G7169B) and fraction collector driver (G7159B).
• Support for the Auto-scale Cluster combining G7158B, G1170A Universal Valve Drive, and 2-position/14-port preparative valve head (5320-0002) for streamlined analytical to preparative scale transitions.
• Expansion of the Pressure Limit Cluster functionality to include 1260 Infinity II pumps, automatically capping system pressure to protect sensitive components.
• Updated default flow ramp settings in G7161A/B preparative binary pumps from 100 to 600 mL/min² for faster method execution.
• Localization extension: Russian language support added alongside existing English, Chinese, Japanese, and Brazilian Portuguese options.
• Compatibility matrix covering supported operating systems (Windows 7 SP1 through Windows 10), supported Chromatographic Data Systems (OpenLab CDS and ChemStation Edition), and recommended firmware versions for all modules.

Main results and discussion

The new module support enables preparative workflows to be fully controlled from the same driver interface, improving method consistency. The Auto-scale cluster facilitates seamless switching between scouting and purification, reducing manual intervention. Enhanced pressure management across both 1260 and 1290 Infinity II pumps improves system safety and longevity. Faster default flow ramps in preparative pumps shorten cycle times without compromising method integrity. Expanded language offerings broaden global usability of the software.

Benefits and practical applications

• Greater flexibility in preparative runs using combined injector and fraction collector control.
• Reduced setup complexity via the Auto-scale cluster for high-throughput purification applications.
• Improved system protection against overpressure events through extended pressure limits.
• Time savings in method development with faster preparative pump flow ramps.
• Enhanced accessibility for multilingual laboratories.

Future trends and potential applications

With ongoing advancements in automated preparative workflows, future driver releases may incorporate AI-driven method optimization and real-time performance analytics. Integration with cloud-based monitoring platforms and expanded support for modular remote operation are anticipated. Continued localization and user-experience enhancements will further democratize advanced chromatography.

Conclusion

Agilent LC & CE Drivers 3.1 delivers strategic hardware support, software improvements, and broadened compatibility, empowering chromatographers to streamline preparative and analytical workflows while ensuring system robustness and global usability. Implementing the recommended firmware and adhering to compatibility requirements will maximize the benefits of this release.

Reference

No literature references were cited in this release note.