Size Exclusion Chromatography Analysis of a Monoclonal Antibody and Antibody Drug Conjugate | LabRulez LCMS_EN
 

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Application NoteBiopharmaHigh Resolution Size ExclusionChromatography Analysis of SmallTherapeutic ProteinsAuthorsSandeep Kondaveeti,Te‑Wei Chu, andAndrew CoffeyAgilent Technologies, Inc.AbstractProtein denaturation processes involving aggregation are among the factorsimpeding the development of stable protein drug formulations. The use of sizeexclusion chromatography (SEC) HPLC for determining purity...
Key words
hmw, hmwmonomer, monomerlmw, lmwsec, secsize, sizeexclusion, exclusionmau, mauretention, retentionprotein, proteinresponse, responsetailing, tailingproteins, proteinsmin, mintherapeutic, therapeuticcsf
Application NoteBiotherapeutics &BiosimilarsAnalysis of Camelid Single-DomainAntibodies Using Agilent AdvanceBioSEC 120 Å 1.9 μm and AdvanceBioHIC ColumnsAuthorsTe-Wei Chu and Greg StaplesAgilent Technologies, Inc.AbstractThis application note describes the use of size exclusion chromatography (SEC)and hydrophobic interaction chromatography (HIC) for the analysis of...
Key words
absorbance, absorbancemau, maugln, glnadvancebio, advancebiovhh, vhhmin, minhic, hicsec, secpyro, pyrotime, timenanobodies, nanobodiessdab, sdabcamelid, camelidglutaminyl, glutaminylnanobody
Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
Key words
mau, maubatch, batchresponseresponse, responseresponseresponse, responsemonomer, monomerdimer, dimeropenlab, openlabagilent, agilentmin, minretention, retentionsecondary, secondaryyour, youradvancebio, advancebiosigmamab, sigmamabbar
Agilent BiocolumnsAggregate/Fragment AnalysisApplication Compendium ContentsBackground2Getting Started3How to Guide - Size Exclusion Chromatography for BiomoleculeAnalysis - 5991-3651EN 4Featured Application NotesElevate Your mAb Aggregate Analysis - 5994-2709EN12222High-Resolution, High-Throughput Size Exclusion ChromatographyAnalysis of Monoclonal Antibodies - 5994-0828EN29Sensitive Native Mass Spectrometry of MacromoleculesUsing Standard Flow LC/MS...
Key words
return, returnsection, sectioncontents, contentsmau, mausec, secinsulin, insulinmin, minsize, sizeprotein, proteinmonomer, monomeradvancebio, advancebiotime, timeexclusion, exclusionaggregates, aggregatesaggregate
 

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Application NoteBiopharmaHigh Resolution Size ExclusionChromatography Analysis of SmallTherapeutic ProteinsAuthorsSandeep Kondaveeti,Te‑Wei Chu, andAndrew CoffeyAgilent Technologies, Inc.AbstractProtein denaturation processes involving aggregation are among the factorsimpeding the development of stable protein drug formulations. The use of sizeexclusion chromatography (SEC) HPLC for determining purity...
Key words
hmw, hmwmonomer, monomerlmw, lmwsec, secsize, sizeexclusion, exclusionmau, mauretention, retentionprotein, proteinresponse, responsetailing, tailingproteins, proteinsmin, mintherapeutic, therapeuticcsf
Application NoteBiotherapeutics &BiosimilarsAnalysis of Camelid Single-DomainAntibodies Using Agilent AdvanceBioSEC 120 Å 1.9 μm and AdvanceBioHIC ColumnsAuthorsTe-Wei Chu and Greg StaplesAgilent Technologies, Inc.AbstractThis application note describes the use of size exclusion chromatography (SEC)and hydrophobic interaction chromatography (HIC) for the analysis of...
Key words
absorbance, absorbancemau, maugln, glnadvancebio, advancebiovhh, vhhmin, minhic, hicsec, secpyro, pyrotime, timenanobodies, nanobodiessdab, sdabcamelid, camelidglutaminyl, glutaminylnanobody
Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
Key words
mau, maubatch, batchresponseresponse, responseresponseresponse, responsemonomer, monomerdimer, dimeropenlab, openlabagilent, agilentmin, minretention, retentionsecondary, secondaryyour, youradvancebio, advancebiosigmamab, sigmamabbar
Agilent BiocolumnsAggregate/Fragment AnalysisApplication Compendium ContentsBackground2Getting Started3How to Guide - Size Exclusion Chromatography for BiomoleculeAnalysis - 5991-3651EN 4Featured Application NotesElevate Your mAb Aggregate Analysis - 5994-2709EN12222High-Resolution, High-Throughput Size Exclusion ChromatographyAnalysis of Monoclonal Antibodies - 5994-0828EN29Sensitive Native Mass Spectrometry of MacromoleculesUsing Standard Flow LC/MS...
Key words
return, returnsection, sectioncontents, contentsmau, mausec, secinsulin, insulinmin, minsize, sizeprotein, proteinmonomer, monomeradvancebio, advancebiotime, timeexclusion, exclusionaggregates, aggregatesaggregate
 

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