Size Exclusion Chromatography Analysis of a Monoclonal Antibody and Antibody Drug ConjugateApplications | 2019 | Agilent TechnologiesInstrumentation
GPC/SEC
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
Key words

 

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Application NoteBiopharmaHigh Resolution Size ExclusionChromatography Analysis of SmallTherapeutic ProteinsAuthorsSandeep Kondaveeti,Te‑Wei Chu, andAndrew CoffeyAgilent Technologies, Inc.AbstractProtein denaturation processes involving aggregation are among the factorsimpeding the development of stable protein drug formulations. The use of sizeexclusion chromatography (SEC) HPLC for determining purity...
Key words
hmw, hmwmonomer, monomerlmw, lmwsec, secsize, sizemau, mauexclusion, exclusionprotein, proteinretention, retentionresponse, responseproteins, proteinstailing, tailingmin, mintherapeutic, therapeuticcsf
Application NoteBiotherapeutics &BiosimilarsAnalysis of Camelid Single-DomainAntibodies Using Agilent AdvanceBioSEC 120 Å 1.9 μm and AdvanceBioHIC ColumnsAuthorsTe-Wei Chu and Greg StaplesAgilent Technologies, Inc.AbstractThis application note describes the use of size exclusion chromatography (SEC)and hydrophobic interaction chromatography (HIC) for the analysis of...
Key words
absorbance, absorbancemau, maugln, glnvhh, vhhadvancebio, advancebiomin, minhic, hicpyro, pyrosec, sectime, timenanobodies, nanobodiescamelid, camelidsdab, sdabglutaminyl, glutaminylnanobody
Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
Key words
mau, maubatch, batchresponseresponse, responseresponseresponse, responsemonomer, monomerdimer, dimeropenlab, openlabsecondary, secondaryagilent, agilentmin, minretention, retentionyour, yoursigmamab, sigmamabadvancebio, advancebiobar
Helpful ‘Hints’ for Protein SEC Success
2021|Agilent Technologies|Presentations
Helpful ‘Hints’ for ProteinSEC SuccessJean LaneApplications EngineerLC columns and consumables technical supportMay 27, 20201 Outline for TalkGetting started•SEC definition, common terminology, and why use it?•Considerations for selecting an SEC column- Pain Points/Challenges for SEC- Importance of Pore Size and Particle Size...
Key words
hints, hintshelpful, helpfulsec, secsuccess, successprotein, proteinpore, poresize, sizeadvancebio, advancebiobuffer, bufferexclusion, exclusionmobile, mobilephase, phasedimer, dimervolume, volumecolumn

Size Exclusion Chromatography Analysis of a Monoclonal Antibody and Antibody Drug ConjugateApplications | 2019 | Agilent TechnologiesInstrumentation
GPC/SEC
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
Key words

 

Similar PDF

Toggle
Application NoteBiopharmaHigh Resolution Size ExclusionChromatography Analysis of SmallTherapeutic ProteinsAuthorsSandeep Kondaveeti,Te‑Wei Chu, andAndrew CoffeyAgilent Technologies, Inc.AbstractProtein denaturation processes involving aggregation are among the factorsimpeding the development of stable protein drug formulations. The use of sizeexclusion chromatography (SEC) HPLC for determining purity...
Key words
hmw, hmwmonomer, monomerlmw, lmwsec, secsize, sizemau, mauexclusion, exclusionprotein, proteinretention, retentionresponse, responseproteins, proteinstailing, tailingmin, mintherapeutic, therapeuticcsf
Application NoteBiotherapeutics &BiosimilarsAnalysis of Camelid Single-DomainAntibodies Using Agilent AdvanceBioSEC 120 Å 1.9 μm and AdvanceBioHIC ColumnsAuthorsTe-Wei Chu and Greg StaplesAgilent Technologies, Inc.AbstractThis application note describes the use of size exclusion chromatography (SEC)and hydrophobic interaction chromatography (HIC) for the analysis of...
Key words
absorbance, absorbancemau, maugln, glnvhh, vhhadvancebio, advancebiomin, minhic, hicpyro, pyrosec, sectime, timenanobodies, nanobodiescamelid, camelidsdab, sdabglutaminyl, glutaminylnanobody
Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
Key words
mau, maubatch, batchresponseresponse, responseresponseresponse, responsemonomer, monomerdimer, dimeropenlab, openlabsecondary, secondaryagilent, agilentmin, minretention, retentionyour, yoursigmamab, sigmamabadvancebio, advancebiobar
Helpful ‘Hints’ for Protein SEC Success
2021|Agilent Technologies|Presentations
Helpful ‘Hints’ for ProteinSEC SuccessJean LaneApplications EngineerLC columns and consumables technical supportMay 27, 20201 Outline for TalkGetting started•SEC definition, common terminology, and why use it?•Considerations for selecting an SEC column- Pain Points/Challenges for SEC- Importance of Pore Size and Particle Size...
Key words
hints, hintshelpful, helpfulsec, secsuccess, successprotein, proteinpore, poresize, sizeadvancebio, advancebiobuffer, bufferexclusion, exclusionmobile, mobilephase, phasedimer, dimervolume, volumecolumn
 

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