Analysis of Peptone Samples Using the Agilent InfinityLab 2D‑LC Solutions with Active Solvent Modulation
Applications | 2019 | Agilent TechnologiesInstrumentation
HPLC, LC/MS, 2D-LC, GPC/SEC, LC/SQ
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsasm, peptone, mau, mhc, peptones, min, research, dimension, breakthrough, heart, sec, cutting, commercial, rplc, hrs, peak, casein, tfa, capacity, sample, second, large, separation, fraction, dad, time, samples, column, first, deck, multiple, hydrolysate, phase, acetonitrile, observed, sampling, resolution, signal, injection, predominantly, dimensions, ionization, probably, mobile, differences, eic, intensity, detection, due, effluent
Similar PDF
The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation
2018|Agilent Technologies|Technical notes
Technical Overview The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation Achieving Improved Resolution and Sensitivity for Challenging Combinations of Separation Conditions Author Sonja Krieger Agilent Technologies, Inc. Abstract A major challenge during method development in two-dimensional liquid chromatography (2D-LC)…
Key words
asm, asmdeck, deckrplc, rplcbreakthrough, breakthroughfocusing, focusinggradient, gradientsolvent, solventeclipse, eclipsecolumn, columndimensional, dimensionalcapillaries, capillarieszorbax, zorbaxmodulation, modulationpeptides, peptidespartial
Determination of Multiple Attributes of Monoclonal Antibodies
2021|Agilent Technologies|Applications
Application Note Biopharma/Pharma Determination of Multiple Attributes of Monoclonal Antibodies Simultaneous and parallel multi-attribute analysis using 3D-LC/MS with 2D multimethod option mAb SEC Size variants Protein A CEX LC/MS mAb Titer Charge variants Mol wt (MW) AA sequence PTM Cell…
Key words
trastuzumab, trastuzumaboriginator, originatorcex, cexmau, mauhmw, hmwhic, hiccho, choprotein, proteinvariants, variantscounts, countsdeconvoluted, deconvolutedclone, cloneclones, clonesmin, minvalve
Direct Analysis of In-Process Oligonucleotides Without Manual Purification
2018|Agilent Technologies|Applications
Application Note Biologics and Biosimilars Direct Analysis of In-Process Oligonucleotides Without Manual Purification Ion-pair reversed-phase LC analysis with online desalting using Agilent InfinityLab 2D-LC Solutions Authors Abstract Sonja Krieger and Clarissa Dickhut Agilent Technologies, Inc. Waldbronn, Germany Oligonucleotides synthesized using…
Key words
oligonucleotides, oligonucleotidesoligonucleotide, oligonucleotiderplc, rplcdesalting, desaltingmau, mauanion, anionpurification, purificationdimensional, dimensionalexchange, exchangeimpairs, impairsfractions, fractionstime, timemanual, manualreversed, reversedobtained
Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS
2020|Agilent Technologies|Applications
Application Note Pharma & Biopharma Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS Authors Gerd Vanhoenacker, Isabel Vandenheede, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) Kortrijk, Belgium Sonja Krieger, Sonja Schneider,…
Key words
mab, mabclone, cloneprotein, proteinsec, secheart, heartcutting, cuttingmau, mautocilizumab, tocilizumabactemra, actemracounts, countsoriginator, originatorsupernatants, supernatantsdimension, dimensionvariants, variantsmain