High-Throughput Lead Discovery with Agilent RapidFire/MS Systems: Analysis of UDP-3-O-(R-3-hydroxymyristoyl)-NAcetylglucosamine Deacetylase (LpxC) | LabRulez LCMS
 

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High-Throughput Lead Discovery withAgilent RapidFire/MS Systems:Analysis of Stearoyl-Coenzyme ADesaturase (SCD)Application NoteAuthorsIntroductionWilliam Lamarr, Lauren Frick,and Peter RyeAgilent Technologies, Inc.Wakefield, MA USAThe RapidFire High-throughput Mass Spectrometry System provides drug discoveryresearchers with mass spectrometry-based, high-throughput screening solutionsfor targets that have proven challenging to...
Key words
rapidfire, rapidfirestearoyl, stearoylscd, scdcoenzyme, coenzymethroughput, throughputdesaturation, desaturationassay, assaydiscovery, discoveryradiometric, radiometricdesaturase, desaturasehigh, highspectrometry, spectrometryintractable, intractableoleoyl, oleoylmass
High-Throughput Analysis ofEpigenetic Targets withAgilent RapidFire/MS Systems:Sirtuin (SIRT) EnzymesApplication NoteAuthorIntroductionPeter Rye, Lauren Frick,and William LaMarrAgilent Technologies, Inc.Wakefield, MA USAHistones and other proteins are subject to a variety of posttranslationalmodifications that regulate a host of biological processes. One such modificationis the...
Key words
rapidfire, rapidfiresirt, sirtsirtuins, sirtuinspeptide, peptidesirtuin, sirtuinsustained, sustaineddirect, directkinetic, kineticsecondary, secondarystudying, studyingmultiple, multiplesubstrate, substratefluorescentlytagged, fluorescentlytaggedproducts, productsdeacetylases
High-Throughput Lead Discoverywith Agilent RapidFire/MS Systems:Analysis of Acetyl-Coenzyme ACarboxylase (ACC)Application NoteAuthorsIntroductionWilliam Lamarr, Lauren Frick,and Peter RyeAgilent Technologies, Inc.Wakefield, MA USAThe RapidFire High-throughput Mass Spectrometry System provides drug discoveryresearchers with mass spectrometry-based high-throughput screening solutionsfor targets that have proven challenging to...
Key words
coenzyme, coenzymerapidfire, rapidfireacc, accacoa, acoaacetyl, acetylcarboxylase, carboxylasecoa, coathroughput, throughputdiscovery, discoveryintractable, intractablemalonyl, malonyllabeling, labelingdifficult, difficultspectrometry, spectrometrymass
A study of SIRT1- and SIRT2‑Mediated Deacetylation
2022|Agilent Technologies|Applications
Application NoteDrug DiscoveryA study of SIRT1- and SIRT2‑MediatedDeacetylationUsing the Agilent RapidFire high-throughput massspectrometry systemAuthorsAbstractPeter Rye,Lauren Frick, andWilliam LamarrAgilent Technologies, Inc.The Agilent RapidFire high-throughput mass spectrometry (MS) system iswell‑suited to screening sirtuins because it obviates the need for labeled substratesand coupled...
Key words
rapidfire, rapidfiresubstrate, substrateenzyme, enzymepeptide, peptidedeacetylation, deacetylationbluesky, blueskyreactions, reactionssirtuins, sirtuinsvelocities, velocitieslinear, linearcourse, courseutility, utilitybinding, bindingassays, assaysmodification
 

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High-Throughput Lead Discovery withAgilent RapidFire/MS Systems:Analysis of Stearoyl-Coenzyme ADesaturase (SCD)Application NoteAuthorsIntroductionWilliam Lamarr, Lauren Frick,and Peter RyeAgilent Technologies, Inc.Wakefield, MA USAThe RapidFire High-throughput Mass Spectrometry System provides drug discoveryresearchers with mass spectrometry-based, high-throughput screening solutionsfor targets that have proven challenging to...
Key words
rapidfire, rapidfirestearoyl, stearoylscd, scdcoenzyme, coenzymethroughput, throughputdesaturation, desaturationassay, assaydiscovery, discoveryradiometric, radiometricdesaturase, desaturasehigh, highspectrometry, spectrometryintractable, intractableoleoyl, oleoylmass
High-Throughput Analysis ofEpigenetic Targets withAgilent RapidFire/MS Systems:Sirtuin (SIRT) EnzymesApplication NoteAuthorIntroductionPeter Rye, Lauren Frick,and William LaMarrAgilent Technologies, Inc.Wakefield, MA USAHistones and other proteins are subject to a variety of posttranslationalmodifications that regulate a host of biological processes. One such modificationis the...
Key words
rapidfire, rapidfiresirt, sirtsirtuins, sirtuinspeptide, peptidesirtuin, sirtuinsustained, sustaineddirect, directkinetic, kineticsecondary, secondarystudying, studyingmultiple, multiplesubstrate, substratefluorescentlytagged, fluorescentlytaggedproducts, productsdeacetylases
High-Throughput Lead Discoverywith Agilent RapidFire/MS Systems:Analysis of Acetyl-Coenzyme ACarboxylase (ACC)Application NoteAuthorsIntroductionWilliam Lamarr, Lauren Frick,and Peter RyeAgilent Technologies, Inc.Wakefield, MA USAThe RapidFire High-throughput Mass Spectrometry System provides drug discoveryresearchers with mass spectrometry-based high-throughput screening solutionsfor targets that have proven challenging to...
Key words
coenzyme, coenzymerapidfire, rapidfireacc, accacoa, acoaacetyl, acetylcarboxylase, carboxylasecoa, coathroughput, throughputdiscovery, discoveryintractable, intractablemalonyl, malonyllabeling, labelingdifficult, difficultspectrometry, spectrometrymass
A study of SIRT1- and SIRT2‑Mediated Deacetylation
2022|Agilent Technologies|Applications
Application NoteDrug DiscoveryA study of SIRT1- and SIRT2‑MediatedDeacetylationUsing the Agilent RapidFire high-throughput massspectrometry systemAuthorsAbstractPeter Rye,Lauren Frick, andWilliam LamarrAgilent Technologies, Inc.The Agilent RapidFire high-throughput mass spectrometry (MS) system iswell‑suited to screening sirtuins because it obviates the need for labeled substratesand coupled...
Key words
rapidfire, rapidfiresubstrate, substrateenzyme, enzymepeptide, peptidedeacetylation, deacetylationbluesky, blueskyreactions, reactionssirtuins, sirtuinsvelocities, velocitieslinear, linearcourse, courseutility, utilitybinding, bindingassays, assaysmodification
 

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