Profiling Glycosylation of Monoclonal Antibodies at Three Levels Using the Agilent 6545XT AdvanceBio LC/Q‑TOF
Applications | 2018 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsglycan, mab, glycoforms, nistmab, quantitation, intact, glycans, agilent, assaymap, advancebio, mapping, bioconfirm, bravo, counts, deconvoluted, released, glycosylation, plrp, subunits, relative, workflow, instantpc, mass, amu, analysis, glycoform, height, monoclonal, fluorescence, fld, sample, acquisition, using, masshunter, glykoprep, peptide, tof, were, major, quant, antibodies, results, accurate, jet, glycopeptide, glycopeptides, heavy, preparation, area, sds
Similar PDF
Glycopeptide Characterization for Various Monoclonal Antibodies Using the Agilent 6545XT AdvanceBio LC/Q-TOF
2019|Agilent Technologies|Applications
Application Note Biotherapeutics and Biosimilars Glycopeptide Characterization for Various Monoclonal Antibodies Using the Agilent 6545XT AdvanceBio LC/Q-TOF Author David L. Wong Agilent Technologies, Inc. Introduction Monoclonal antibodies (mAbs) and their derivatives represent a very complex but important class of biopharmaceutical…
Key words
glycopeptides, glycopeptidesmapping, mappingglycan, glycanglycopeptide, glycopeptidemab, mabadvancebio, advancebiopeptide, peptideassaymap, assaymapbravo, bravotkpreeqynstyr, tkpreeqynstyrhilic, hilicpeptides, peptideswere, weremabs, mabscolumn
A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS
2020|Agilent Technologies|Applications
Application Note Pharma & Biopharma A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS Author Brian Liau Agilent Technologies, Inc. Introduction Recent years have witnessed a rapid increase in the…
Key words
innovator, innovatorglycan, glycanglycans, glycansmab, mabsubunits, subunitsreleased, releasedcounts, countsassaymap, assaymapides, idesintact, intactagilent, agilentbravo, bravodeconvoluted, deconvolutedmass, massadvancebio
Agilent BioHPLC Columns - Characterization of NIST Monoclonal Antibody Critical Quality Attributes - Application Compendium
2019|Agilent Technologies|Guides
Agilent BioHPLC Columns Characterization of NIST Monoclonal Antibody Critical Quality Attributes Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…
Key words
mab, mabglycan, glycanadvancebio, advancebiocounts, countsmapping, mappingpeptide, peptideagilent, agilentmonoclonal, monoclonalglycans, glycansmin, mincolumn, columnmass, massprotein, proteinnistmab, nistmabassaymap
Glycan Analysis - Agilent BioHPLC Columns Application Compendium
2020|Agilent Technologies|Guides
Agilent-NISTmAb Glycan Analysis Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge variants…
Key words
glycan, glycanpage, pagecontents, contentsback, backglycans, glycansadvancebio, advancebiomab, mabinstantpc, instantpcmapping, mappingfld, fldmonoclonal, monoclonaleluent, eluentagilent, agilenthilic, hilicfluorescence