A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS | LabRulez LCMS_EN
 

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Agilent-NISTmAbIntact & Subunit AnalysisUsing Reversed PhaseAgilent BioHPLC ColumnsApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass information....
Key words
counts, countsmab, mabintact, intactherceptin, herceptinpage, pagecontents, contentsbonds, bondsback, backdeglycosylated, deglycosylatedmass, massdeconvoluted, deconvolutedides, idesamu, amubravo, bravoassaymap
An Integrated Workflow for Intactand Subunits of Monoclonal AntibodyAccurate Mass MeasurementsApplication NoteBiotherapeutics and BiosimilarsAuthorsIntroductionShuai Wu and Maryann ShenMonoclonal antibody (mAb) based entities represent a rapidly growing class ofbiologics that require extensive characterization to obtain approval for clinical trials andsubsequent market...
Key words
counts, countsmab, mabherceptin, herceptinbonds, bondsdeglycosylated, deglycosylatedides, idesassaymap, assaymapnist, nistbravo, bravoantibody, antibodyintact, intactaffinity, affinitymass, massdeconvoluted, deconvolutedcartridge
Application NoteBiotherapeutics andBiosimilarsProfiling Glycosylation of MonoclonalAntibodies at Three Levels Using theAgilent 6545XT AdvanceBio LC/Q‑TOFAuthorIntroductionDavid L. WongAgilent Technologies, Inc.Santa Clara, CA, USAMonoclonal antibodies (mAbs) and their derivatives represent a very important classof biopharmaceutical molecules with a wide range of applications. With...
Key words
glycan, glycanglycoforms, glycoformsmab, mabnistmab, nistmabquantitation, quantitationintact, intactglycans, glycansagilent, agilentmapping, mappingadvancebio, advancebioassaymap, assaymapbioconfirm, bioconfirmbravo, bravocounts, countsdeconvoluted
Agilent BioHPLC ColumnsCharacterization of NIST MonoclonalAntibody Critical Quality AttributesApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass...
Key words
mab, mabglycan, glycanadvancebio, advancebiomapping, mappingcounts, countspeptide, peptideagilent, agilentmonoclonal, monoclonalglycans, glycansmin, minprotein, proteinmass, massnistmab, nistmabcolumn, columnassaymap
 

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Agilent-NISTmAbIntact & Subunit AnalysisUsing Reversed PhaseAgilent BioHPLC ColumnsApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass information....
Key words
counts, countsmab, mabintact, intactherceptin, herceptinpage, pagecontents, contentsbonds, bondsback, backdeglycosylated, deglycosylatedmass, massdeconvoluted, deconvolutedides, idesamu, amubravo, bravoassaymap
An Integrated Workflow for Intactand Subunits of Monoclonal AntibodyAccurate Mass MeasurementsApplication NoteBiotherapeutics and BiosimilarsAuthorsIntroductionShuai Wu and Maryann ShenMonoclonal antibody (mAb) based entities represent a rapidly growing class ofbiologics that require extensive characterization to obtain approval for clinical trials andsubsequent market...
Key words
counts, countsmab, mabherceptin, herceptinbonds, bondsdeglycosylated, deglycosylatedides, idesassaymap, assaymapnist, nistbravo, bravoantibody, antibodyintact, intactaffinity, affinitymass, massdeconvoluted, deconvolutedcartridge
Application NoteBiotherapeutics andBiosimilarsProfiling Glycosylation of MonoclonalAntibodies at Three Levels Using theAgilent 6545XT AdvanceBio LC/Q‑TOFAuthorIntroductionDavid L. WongAgilent Technologies, Inc.Santa Clara, CA, USAMonoclonal antibodies (mAbs) and their derivatives represent a very important classof biopharmaceutical molecules with a wide range of applications. With...
Key words
glycan, glycanglycoforms, glycoformsmab, mabnistmab, nistmabquantitation, quantitationintact, intactglycans, glycansagilent, agilentmapping, mappingadvancebio, advancebioassaymap, assaymapbioconfirm, bioconfirmbravo, bravocounts, countsdeconvoluted
Agilent BioHPLC ColumnsCharacterization of NIST MonoclonalAntibody Critical Quality AttributesApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass...
Key words
mab, mabglycan, glycanadvancebio, advancebiomapping, mappingcounts, countspeptide, peptideagilent, agilentmonoclonal, monoclonalglycans, glycansmin, minprotein, proteinmass, massnistmab, nistmabcolumn, columnassaymap
 

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