Semi-Quantitative Mapping of Oncological Therapies with Mass Spectrometry ImagingPosters | 2019 | WatersInstrumentationIon Mobility, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MSIndustriesClinical ResearchManufacturerWatersKey wordsdxr, imaging, maldi, doxorubicin, msi, intensities, chemoembolization, explanted, generosity, lipiodol, microcatheter, tace, transarterial, tissue, oncological, mimetic, catheter, inhomogeneity, using, recurrence, hcc, hepatocellular, cancers, carcinoma, through, hdi, pig, were, mass, funding, pipetted, therapies, emulsion, advancing, homogenizer, branch, administered, signal, extracted, bead, correlate, treat, occurrence, quantitative, homogenized, liver, preliminary, spectrometry, thoroughly, characterized
TIMS enabled quantification of small molecules in MALDI Imaging
TIMS enabled quantification of small moleculesin MALDI ImagingtimsTOF fleX was used to demonstrate quantitative mass spectrometry imaging onseveral drug compounds.AbstracttimsTOF fleX was able to separatenear-isobaric ions by their ionmobilities, significantly improvingtargeted compound specificityand sensitivity for quantitation in acomplex molecular environment.Higher...
timstof, timstofflex, flextims, timsmaldi, maldiions, ionsisobaric, isobaricgadavist, gadavistqmsi, qmsitopotecan, topotecanimaging, imagingtissue, tissuemmae, mmaeintensity, intensitydrug, drugpasef
QUANTITATIVE IMAGING MASS SPECTROMETRY OF ENDOGENOUS METABOLITES USING IN-LINE INTERNAL STANDARDS AND STABLE ISOTOPE LABELED MIMETIC MODEL
QUANTITATIVE IMAGING MASS SPECTROMETRY OF ENDOGENOUS METABOLITES USING IN-LINEINTERNAL STANDARDS AND STABLE ISOTOPE LABELED MIMETIC MODELBindesh Shrestha,1 Khaja Muneeruddin,2 Scott A. Shaffer21Waters Corporation, Beverly, MA 1Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical SchoolINTRODUCTION•Quantitative spatial distributions of small...
imaging, imagingdesi, desimimetic, mimeticinaccessible, inaccessiblemetabolites, metabolitespixel, pixeltissue, tissuemolecules, moleculesmaldi, maldiendogenous, endogenousexogeneous, exogeneousquantiation, quantiationfuture, futuremass, massquantitative
Ovarian Cancerous Tissue Identification by DESI Imaging for Clinical Research
[ TECHNOLOGY BRIEF ]Ovarian Cancerous Tissue Identification byDESI Imaging for Clinical ResearchLuisa Doria,1 Emmanuelle Claude, 2 and Zoltan Takats1Imperial College, London, UK; 2Waters Corporation, Wilmslow, UK1The use of DESI can help distinguish between severaldifferent tissue types in ovarian cancer samples...
desi, desitissue, tissueovarian, ovariantumor, tumorstroma, stromamsi, msiimages, imagesimaging, imagingstained, stainedcancer, cancerrois, roiscarcinoma, carcinomasupervised, supervisedbrief, briefassociated
APPLICATION NOTEBOOK - MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS
[ APPLICATION NOTEBOOK ]MS IMAGING AND AMBIENT IONIZATION-MSFOR METABOLOMICS AND LIPIDOMICS1This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245ENTABLE OF CONTENTS3 Introduction4 Biomarker Discovery Directly from Tissue Xenograph Using High Definition ImagingMALDI Combined with Multivariate...
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectiondefinition, definitionmobility, mobilityion, ionhdms, hdmsimage, imagebiomarker, biomarkerspatial, spatialxenograph, xenographdata