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METHOD DEVELOPMENT OF IONIC-STRENGTH GRADIENT CATION EXCHANGE CHROMATOGRAPHY FOR MONOCLONAL ANTIBODY CHARGE VARIANT ANALYSIS

 

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[ APPLICATION NOTE ] Development of Monoclonal Antibody Charge Variant Analysis Methods Using a BioResolve SCX mAb Column Hua Yang, Bill Warren, and Stephan Koza Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Method development parameters for cation Charge heterogeneity…
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[ APPLICATION NOTE ] Development of pH Gradient Mobile Phase Concentrates for Robust, High Resolution mAb Charge Variant Analysis Qi Wang, Susan C. Rzewuski, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Platform method…
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Application News No. AD-0227 Biopharma / Nexera Bio UHPLC / Shim-pack Bio IEX Exploring Factors That Influence Charge Variant Analysis of mAbs with Shim-packTM Bio IEX Columns using Salt Gradient Elution ❑ Introduction Protein-based therapeutic drugs including monoclonal antibodies (mAbs)…
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Agilent Biocolumns Charge Variant Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Ion-Exchange Chromatography for Biomolecule Analysis - 5991-3775EN 4 Featured Application Notes 22 Convenient Customization of Your Cation Exchange Analysis 5994-3257EN  22 How…
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